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ProteomicsInteraction network of the Cysteine Repeat Modular protein complex of Toxoplasma gondii
Apicomplexa are obligate intracellular parasites. While most species are restricted to specific hosts and cell types, Toxoplasma gondii can invade every nucleated cell derived from warm-blooded animals. This broad host range suggests that this parasite can recognize multiple host cell ligands or str...
ORGANISM(S): Toxoplasma gondii RH 
2023-01-30 | PXD035654 | Pride
Turboid Crmps Dicre Invasion Toxoplasma 
ProteomicsIdentification of interaction partners of the Toxoplasma gondii Cysteine Repeat Modular Proteins TGGT1_292020 and TGGT1_261080
Apicomplexa are obligate intracellular parasites. While most species are restricted to specific hosts and cell types, Toxoplasma gondii can invade every nucleated cell derived from warm-blooded animals. This broad host range suggests that this parasite can recognize multiple host cell ligands or str...
ORGANISM(S): Toxoplasma gondii RH 
2022-12-13 | PXD031649 | Pride
Crmps Turboid Toxoplasma gondii Pulldown Apicomplexa 
ProteomicsBioID of the proteins CGP and FRM1 from Toxoplasma gondii
The conoid complex, a unique structure in the phylum Apicomplexa, is crucial for host cell invasion, egress, and motility. Despite its importance, the detailed molecular composition and assembly mechanisms of the conoid complex remain poorly understood. In previous research, we identified an essenti...
ORGANISM(S): Toxoplasma gondii RH 
2025-09-17 | PXD053452 | Pride
Interactor Conoid complex Toxoplasma gondii Cgp Frm1 
ProteomicsToxoplasma Tepsin is essential for transport from the trans-Golgi to the vacuole
Apicomplexans are intracellular parasites that invade and replicate within host cells. During their adaptation to this parasitic life-style these protozoans evolved numerous new organelles. Paradoxically, these parasites lost several cellular machineries which are conserved in other eukaryotes, inc...
ORGANISM(S): Toxoplasma gondii RH 
2025-10-14 | PXD057662 | Pride
Toxoplasma gondii Tepsin Vesicular trafficking Adaptor protein 4 
ProteomicsThe role of methylation in egress and motility initiation in Toxoplasma gondii
Apicomplexan parasites such as Toxoplasma gondii depend on finely tuned cytoskeletal dynamics to invade and exit host cells. A central structure in this process is the conoid, a dynamic apical microtubule-based scaffold that integrates signalling and structural cues to initiate motility. While the l...
ORGANISM(S): Toxoplasma gondii RH 
2026-08-24 | PXD067879 | Pride
Akmt Toxoplasma gondii Motility initiation Apical methylation Pckmt 
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