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ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 3 - controls (5/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002260 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 1 - biological replicates (2/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002257 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 2 - controls (3/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002258 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 3 - biological replicates (6/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002261 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 1 - controls (1/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002256 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 4 - controls (7/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002262 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 4 - biological replicates (8/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002263 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins interacting with extracellularly applied α-syn assemblies, Condition 2 - biological replicates (4/8)
Fibrillar α-Synuclein (α-Syn) is the principal component of Lewy bodies which are evident in individuals affected by Parkinson disease (PD). This neuropathologic form of α-Syn contributes to PD progression and propagation of exogeneous α-Syn between neurons has been demonstrated. In order to identif...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-07 | PXD002259 | Pride
Lc-msms Oligomers Fibrils Pull-down Protein-protein interactions Proteomics Alpha-synuclein 
ProteomicsIdentification of proteins that interact with extracellularly applied fibrillar Tau assemblies
The microtubule associated protein Tau (MAPT) expressed in neurons is involved in microtubules stabilization, cell morphogenesis and axonal transport. In pathological conditions, Tau assembles into high molecular weight assemblies leading to neuropathological Tau deposits, the hallmark of several n...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-09 | PXD009294 | Pride
Lc-msms Pull-down 1n4r isoform Interacting protein partners Tau fibrils Proteomics 1n3r isoform 
UnknownLAG3 is not expressed in human and murine neurons and does not modulate ?-synucleinopathies
Not available
S-SCDT-EMM-2021-14745 | biostudies-other
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