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ProteomicsGlobal Membrane Protein Interactome Analysis using In vivo Crosslinking and MS-based Protein Correlation Profiling
We present a methodology using in vivo crosslinking combined with HPLC-MS for the global analysis of endogenous protein complexes by protein correlation profiling. Formaldehyde crosslinked protein complexes were extracted with high yield using denaturing buffers that maintained complex solubility du...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-02 | MSV000080014 | MassIVE
GenomicsX-chromosome dynamics revealed by the RNA interactome and chromosomal binding of CTCF
CTCF is a master regulator that plays a role in genome architecture and gene expression. A key aspect of CTCF’s mechanism involves bringing together distant genetic elements for intra- and inter-chromosomal interactions. Evidence from epigenetic processes, such as X-chromosome inactivation (XCI), su...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-58242 | biostudies-arrayexpress
TranscriptomicsA comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
The inactive X chromosome (Xi) serves as a model to understand gene silencing on a global scale. Here, we perform identification of direct RNA interacting proteins? (iDRiP) to isolate a comprehensive protein interactome for Xist, an RNA required for Xi silencing. We discover multiple classes of inte...
ORGANISM(S): Mus musculus 
2015-06-19 | E-GEOD-67516 | biostudies-arrayexpress
TranscriptomicsInteractome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a host transcriptome response, we performed genom...
ORGANISM(S): Macaca fascicularis 
2010-03-18 | E-GEOD-20262 | biostudies-arrayexpress
ProteomicsA Rab1 interactome illuminates its dual role in autophagy and membrane trafficking
The small GTPase Rab1 is found in all eukaryotes and acts in both ER-to-Golgi transport and autophagy. Several Rab1 effectors and regulators have been identified, but the mechanism by which Rab1 orchestrates these distinct processes remains incompletely understood. We apply MitoID, a proximity bioti...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD065220 | Pride
Membrane trafficking Autophagy Rab1 Interactome 
ProteomicsCombining proximity labeling and crosslinking mass spectrometry for proteomic dissection of nuclear envelope interactome
Analysis of LAP1 interactome in HEK293T cells using proximity labeling or proximity labeling combined with crosslinking methods.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-20 | MSV000084606 | MassIVE
ProteomicsVAP-mediated membrane tethering mechanisms implicate ER-PM contact function in pH homeostasis
MS analyses of interactome of full-length (i.e., Scs2 and Scs22) and TM-truncated (i.e., Scs2N and Scs22N) fission yeast VAPs.
ORGANISM(S): Schizosaccharomyces Pombe (fission Yeast) 
2024-08-09 | PXD053887 | JPOST Repository
UnknownThe liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus.
Not available
S-EPMC3714164 | biostudies-literature
UnknownSpatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons.
Not available
S-EPMC11868546 | biostudies-literature
UnknownA membrane protein display platform for receptor interactome discovery.
Not available
S-EPMC8488672 | biostudies-literature
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