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TranscriptomicsTemporal response of DCs to LPS stimulation: 4sU_sequencing
Regulation of RNA levels is critical for the response to external stimuli and determined through the interplay between RNA production, processing and degradation. Despite the centrality of these processes, most global studies of RNA regulation do not distinguish their separate contributions and rela...
ORGANISM(S): Mus musculus 
2011-04-24 | E-GEOD-25432 | biostudies-arrayexpress
Unknown13C metabolic flux analysis of microbial and mammalian systems is enhanced with GC-MS measurements of glycogen and RNA labeling.
Not available
S-EPMC5845444 | biostudies-literature
ProteomicsRNP remodeling during RNA virus replication through phosphoregulation of SR proteins revealed by metabolic labeling
Mechanisms used by positive-stranded RNA viruses to control the translation-replication switch remain largely unexplored. Using metabolic labeling coupled with quantitative proteomics analyses, we unraveled the protein composition of temporal ribonucleoprotein complexes (RNPs) isolated during early ...
ORGANISM(S): Homo sapiens (Human) Enterovirus A71 
2025-06-04 | PXD036890 | Pride
4su labeling Ev-a71 Ribonucleotide protein Sr protein 
UnknownMetabolic RNA labeling for probing RNA dynamics in bacteria.
Not available
S-EPMC7736802 | biostudies-literature
TranscriptomicsQuiescent Fibroblasts Exhibit High Metabolic Activity
Many cells in mammals exist in the state of quiescence, which is characterized by reversible exit from the cell cycle. Quiescent cells are widely reported to exhibit reduced size, nucleotide synthesis, and metabolic activity. Much lower glycolytic rates have been reported in quiescent compared with ...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-42612 | biostudies-arrayexpress
GenomicsHalfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives
Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives
PRJNA1166201 | ENA
MetabolomicsA pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella

Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open question due to the difficulties in distinguishing between bacterial and host metabolites

2023-08-02 | MTBLS1275 | MetaboLights
UnknownSynthesis of 4-thiouridines with prodrug functionalization for RNA metabolic labeling.
Not available
S-EPMC8985182 | biostudies-literature
UnknownGenome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling.
Not available
S-EPMC7605262 | biostudies-literature
TranscriptomicsMetabolic syndrome exercise training
We assessed vastus lateralis muscle gene expression levels of 12 women with the metabolic syndrome before and after a 6 month exercise training program RNA was isolated from a vastus lateralis muscle biopsy of 6 women with the metabolic syndrome before and after a 6 month guided endurance exercise t...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-43760 | biostudies-arrayexpress
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