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TranscriptomicsMiRNome profiling in metachronous colorectal liver metastasis
Small RNA sequencing was performed on 43 metachronous colorectal liver metastases (mCLM) and adjacent non-malignant liver tissue sample pairs to identify deregulated miRNAs. MiRNA-mRNA interactions were investigated through co-expression and correlation analysis, with prognostic relevance assessed b...
ORGANISM(S): Homo sapiens 
2026-01-12 | E-MTAB-15020 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling in metachronous colorectal liver metastasis
Differential expression analysis was performed on 36 metachronous colorectal liver metastases (mCLM) and adjacent non-malignant liver tissue sample pairs to identify deregulated genes. GSEA and CMS classification were used to explore pathways and stratify tumors. miRNA-mRNA interactions were investi...
ORGANISM(S): Homo sapiens 
2026-01-12 | E-MTAB-15022 | biostudies-arrayexpress
ProteomicsDifferential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer
Colorectal cancer (CRC) patients suffer from the second highest mortality among all cancer entities. In half of all CRC patients, colorectal cancer liver metastases (CRLM) can be observed. Metastatic colorectal cancer is associated with poor overall survival and limited treatment options. Even after...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020109 | Pride
Ecm Prognostic factor Colorectal liver metastasis Crlm Proteomics Colorectal cancer Ecm signatures Metachronous liver metastasis Crc Extracellular matrix Lc-ms/ms 
GenomicsMiRNome profiling in metachronous colorectal liver metastasis
MiRNome profiling in metachronous colorectal liver metastasis
PRJEB88377 | ENA
GenomicsRNA-seq profiling in metachronous colorectal liver metastasis
RNA-seq profiling in metachronous colorectal liver metastasis
PRJEB88378 | ENA
UnknownSLC14A1 and TGF-β signaling: a feedback loop driving EMT and colorectal cancer metachronous liver metastasis.
Not available
S-EPMC11282742 | biostudies-literature
ClinicalEarly Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection
In this study, the Quintuple method was applied for early intervention of prehepatic CTC-positive bowel cancer patients without dominant liver metastasis, aiming to explore the blocking effect of the Quintuple method on the metachronous liver metastases of colorectal cancer. A one-arm randomized cli...
7762 | ecrin-mdr-crc
UnknownDevelopment and validation of a TRIM27-based nomogram for predicting metachronous liver metastasis and prognosis in postoperative colorectal cancer patients.
Not available
S-EPMC11396292 | biostudies-literature
UnknownPrealbumin predicts metachronous liver metastasis in colorectal cancer.
Not available
S-EPMC12751164 | biostudies-literature
UnknownPancreatic ductal adenocarcinoma with synchronous and metachronous hepatic metastasis predicted by contrast-enhanced ultrasound.
Not available
S-EPMC10240015 | biostudies-literature
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