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ProteomicsNeprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
Muscle contraction depends on strictly controlled Ca2+ transients within myocytes. A major player maintaining these transients is the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase, SERCA. Activity of SERCA is regulated by binding of micropeptides and impaired expression or function of these peptide...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-06-01 | PXD027738 | Pride
Neprilysin Calcium homeostasis Metallopeptidase Micropeptides Serca Heart physiology Drosophila melanogaster 
TranscriptomicsSeasonal RNAseq of Antarctic krill, Euphausia superba, from three different latitudinal regions of the Southern Ocean
The experiment aimed to investigate seasonal and regional differences in gene expression in Antarctic krill in three different latitudinal regions of the Southern Ocean with variable photoperiodic conditions: South Georgia (54°S), South Orkneys/Bransfield Strait (60°S-63°S) and Lazarev Sea (62°S -66...
ORGANISM(S): Euphausia superba 
2020-08-12 | E-MTAB-7467 | biostudies-arrayexpress
UnknownIsolation and Characterization of a Theta Glutathione S-transferase Gene from Panax ginseng Meyer.
Not available
S-EPMC3659607 | biostudies-literature
MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
TranscriptomicsTranscriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii
Two S. rolfsii transcriptomes obtained from scleroglucan-producing and scleroglucan-nonproducing conditions were pooled and sequenced using the 454 pyrosequencing technique yielding ~350,000 reads. These could be assembled into 21,937 contigs and 171,833 singletons, for which 6,951 had significant m...
ORGANISM(S): Athelia rolfsii 
2010-05-15 | E-GEOD-21040 | biostudies-arrayexpress
UnknownA Molecular Low-Coordinate [Fe-S-Fe] Unit in Three Oxidation States.
Not available
S-EPMC8048577 | biostudies-literature
UnknownIsostructural bridging diferrous chalcogenide cores [FeII(μ-E)FeII] (E = O, S, Se, Te) with decreasing antiferromagnetic coupling down the chalcogenide series.
Not available
S-EPMC10283490 | biostudies-literature
MetabolomicsPREDICT: untargeted metabolomic profiling in a Brassica napus (canola) breeding population by GC-MS

Genome-wide association studies (GWAS) identified thousands of genetic loci associated with complex plant traits, including many traits of agronomical importance. However, functional interpretation of GWAS results remains challenging because of large candidate regions due to linkage disequilibriu...

2023-11-20 | MTBLS8056 | MetaboLights
UnknownIdentification and characterization of the mediator kinase-dependent myometrial stem cell phosphoproteome.
Not available
S-EPMC10906282 | biostudies-literature
UnknownTwo Prevalent ∼100-kb GYPB Deletions Causative of the GPB-Deficient Blood Group MNS Phenotype S-s-U- in Black Africans.
Not available
S-EPMC7443675 | biostudies-literature
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