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ProteomicsScreening for micropeptides in HUVEC without tryptic digestion, part 1
Long non-coding RNAs (lncRNA) are transcribed but not translated ribonucleic acids with various functions. We analyzed a so far unreported lncRNA n342419, which we named MANTIS. A search for micropeptides after overexpression of MANTIS in Human Umbilical Vein Endothelial Cells (HUVEC) with subsequen...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD005951 | Pride
Lncrna Micropeptides Lc-msms 
ProteomicsScreening for micropeptides in HUVEC with tryptic digestion, part 2
Long non-coding RNAs (lncRNA) are transcribed but not translated ribonucleic acids with various functions. We analyzed a so far unreported lncRNAn 342419, which we named MANTIS. A search for micropeptides after overexpression of MANTIS in Human Umbilical Vein Endothelial Cells (HUVEC) with subsequen...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD005957 | Pride
Lncrna Micropeptides Lc-msms 
GenomicsViral infection identifies micropeptides differentially regulated in smORF-containing lncRNA
Viral infection identifies micropeptides differentially regulated in smORF-containing lncRNA
PRJNA395384 | ENA
UnknownMicropeptides translated from putative long non-coding RNAs.
Not available
S-EPMC9827906 | biostudies-literature
GenomicsTranslation and Natural Selection of long non-canonical RNA micropeptides
Translation and Natural Selection of long non-canonical RNA micropeptides
PRJNA842067 | ENA
ProteomicsNeprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
Muscle contraction depends on strictly controlled Ca2+ transients within myocytes. A major player maintaining these transients is the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase, SERCA. Activity of SERCA is regulated by binding of micropeptides and impaired expression or function of these peptide...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-06-01 | PXD027738 | Pride
Neprilysin Calcium homeostasis Metallopeptidase Micropeptides Serca Heart physiology Drosophila melanogaster 
TranscriptomicsIdentification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation
Identification of the coding elements in the genome is a fundamental step to understanding the building blocks of living systems. Short peptides (< 100 aa) have emerged as important regulators of development and physiology, but their identification has been limited by their size. We have leveraged t...
ORGANISM(S): Danio rerio 
2014-04-04 | E-GEOD-53693 | biostudies-arrayexpress
UnknownWidespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.
Not available
S-EPMC5696797 | biostudies-literature
UnknownNeprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides.
Not available
S-EPMC9338278 | biostudies-literature
TranscriptomicsViral infection identifies micropeptides differentially regulated in smORF-containing lncRNA
We use genome-wide high-throughput methods to identify potential micropeptides in smORF containing lncRNA involved in the immune response. Using influenza as a viral infection model, we performed RNAseq and ribosome profiling to track expression and translation of putative lncRNAs that encode for pe...
ORGANISM(S): Influenza A virus (A/reassortant/NIBRG-121(California/07/2009 x PR8)(H1N1)) Homo sapiens 
2017-07-31 | GSE101760 | GEO
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