Skeletal myocyte differentiation involves fusion of myoblasts to multinucleated myotubes. In vitro differentiation can be induced by serum withdrawal. The differentiation process is negatively regulated by pathological concentrations of TNF-alpha but can be positively regulated by IGF1. This study f...
This model is from the article:
Dynamics and feedback loops in the transforming growth factor β signaling pathway.
Wegner K, Bachmann A, Schad JU, Lucarelli P, Sahle S, Nickel P, Meyer C, Klingmüller U, Dooley S, Kummer U. Biophys Chem.
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Data from ProteomeXchange, PXD ID: PXD001514. File: CSF124WT_50cm_TR1.mzml. Published as part of Mol Cell Proteomics. 2015 Oct;14(10):2550-63 . From the Abstract: {{i}} ... We demonstrate that the CSF proteome of individual mice can be analyzed in a quantitative manner to a depth of several hundred...
The iTRAQ 4-plex experiment was carried out with 2 biological replicates of untreated HEK cells (114 and 116 label) and 2 biological replicates of HEK cells treated with geneticin (16 µM) for 32 h (115 and 117 label).
