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TranscriptomicsTranscription profiling of human T-ALL patients at diagnosis and relapse
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 104 samples; Affymetrix U133A micro-arrays.

Ninety two patients with T-ALL were diagnosed and treated at Saint-Louis hospital, Paris. Seven patients were studied a...
ORGANISM(S): Homo sapiens 
2005-04-15 | E-MEXP-313 | biostudies-arrayexpress
ProteomicsTransfer of antigen target into CAR T cells via trogocytosis
To characterize transfer of molecules from target cells into CAR T cells via trogocytosis we cultured NALM-6 leukemia cell line expressing a CD19-mCherry fusion protein with CAR T cells. NALM6-CD19-mCherry were loaded with heavy amino acid and cocultured with CAR T cells for 1 hour. CAR T cells wer...
ORGANISM(S): Homo sapiens (Human) 
2019-03-29 | PXD012833 | Pride
T cell Car t cell Leukemia Trogocytosis Cd19 
TranscriptomicsCAR-adapted PIK3CD base editing enhances T cell anti-tumor potency
Insufficient functional T cell persistence impedes therapeutic success of chimeric antigen receptor (“CAR”) therapies. Here, we performed a CAR-adapted base editing screen of PIK3CD, a key regulator of T cell function, metabolism, and fate. We identified point mutations that beneficially modulate CA...
ORGANISM(S): Homo sapiens 
2025-11-06 | E-MTAB-15749 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fetal gammadelta T cells from that cytomegalovirus (CMV) positive or negative
Response of fetal gammadelta T cells towards infection with human cytomegalovirus (CMV)
ORGANISM(S): Homo sapiens 
2009-12-12 | E-MEXP-2055 | biostudies-arrayexpress
TranscriptomicsT cell help controls the speed of the cell cycle in germinal center B cells.
The germinal center (GC) is a microanatomical compartment wherein high-affinity antibody-producing B cells are selectively expanded. B cells proliferate and mutate their antibody genes in the dark zone (DZ) of the GC and are then selected by T cells in the light zone (LZ) on the basis of affinity. H...
ORGANISM(S): Mus musculus 
2015-08-12 | E-GEOD-71295 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse CD8 T cells in response to P1A antigen expressing tumor cells or cells not expressing 1A antigen
Activation status of CD8 T cells in response to a tumor challenge. Although both natural killer (NK) cells and CD8 T cells are capable of anti-tumor responses, Recombinase Activating Gene (RAG)-deficient mice, which have a normal component of NK cells, are incapable of rejecting the P815 mastocytoma...
ORGANISM(S): Mus musculus 
2007-12-01 | E-MEXP-1285 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NK cells in presence/absence of activated CD8 T cells
we compare NK cells in presence of activated CD8 T cells or not. Although both natural killer (NK) cells and CD8 T cells are capable of anti-tumor responses, Recombinase Activating Gene (RAG)-deficient mice, which have a normal component of NK cells, are incapable of rejecting the P815 mastocytoma t...
ORGANISM(S): Mus musculus 
2007-11-01 | E-MEXP-1284 | biostudies-arrayexpress
TranscriptomicsExpression data from T lymphocytes derived from T-iPS and peripheral blood
T lymphocytes can be generated from T-cell-derived induced pluripotent stem cells (T-iPS). We used microarrays to better elucidate their phenotype and compare their gene expression profile to that of known lymhoid subsets from peripheral blood. Total mRNA was extracted from T-iPS-derived T cells at ...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-47920 | biostudies-arrayexpress
ProteomicsExpanding the MAPPs assay to accommodate MHC-II pan re-ceptors for improved predictability of potential T cell epitopes
The appended raw files, csv files and other documents were deposited in the public domain in support for the publication "Expanding the MAPPs assay to accommodate MHC-II pan re-ceptors for improved predictability of potential T cell epitopes" by Katharina Hartman, Guido Steiner, Michel Siegel, Cary ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-25 | MSV000092747 | MassIVE
ProteomicsMicrobial metabolite Indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation
The gut microbiota and its metabolites critically regulate immune cell phenotype, function, and energy metabolism. We screened a collection of gut microbiota-related metabolites to identify modulators of mitochondrial metabolism in T cells. Here, we show that indole-3-propionic acid (IPA) stimulates...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-28 | PXD057537 | Pride
Gut microbiota Indole-3-propionic acid (ipa) Immunometabolism Inflammatory bowel disease (ibd) Cd4+ t cell 
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