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UnknownHypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide.
Not available
S-EPMC2745664 | biostudies-literature
UnknownDifferential regulation of Rhizobium etli rpoN2 gene expression during symbiosis and free-living growth.
Not available
S-EPMC107331 | biostudies-literature
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20712 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data 2)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22249 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (HCT116 cell line data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20868 | biostudies-arrayexpress
ProteomicsNovel autoantibodies in rheumatoid arthritis using immunoprecipitation coupled with mass spectrometric analysis.
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint inflammation resulting in progressive cartilage and bone destruction. In two thirds of early RA patients, rheumatoid factor (RF) and/or anti-citrullinated protein antibodies (ACPAs) are present. While these ant...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD069628 | Pride
Anti nuclear antibodies Mass spectrometry Ipms Rheumatoid arthritis Autoantibodies 
ProteomicsPKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs
Eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), better known as PKR plays a key role in the response to viral infections and cellular homeostasis by regulating mRNA translation. Upon binding dsRNA, PKR is activated through homodimerization and subsequent autophosphorylation on T...
ORGANISM(S): Homo sapiens (Human) 
2021-05-10 | PXD022564 | Pride
Dsrna binding Viral infection Pkr Autophosphorylation Regulation 
UnknownProton irradiation orchestrates macrophage reprogramming through NFκB signaling.
Not available
S-EPMC6021396 | biostudies-literature
ProteomicsThe ITM2B-associated retinal dystrophy mutation modifies BRI23 peptide interactions in the human retina
BRI23, composed of the 23 last amino acids of the integral transmembrane protein 2B (ITM2B) C-terminus, is associated with several neurodegenerative diseases, including retinal dystrophy (RD) and familial dementia. Its role in the retina remains poorly understood. This study provides a comprehensive...
ORGANISM(S): Homo sapiens (Human) 
2025-07-25 | PXD060682 | Pride
Bri23 Retina Retinal dystrophy Protein interactions Itm2b 
TranscriptomicsComparative genomic hybridization of human hepatoblastomas identifies two tumor subclasses resembling distinct phases of liver development
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Hepatoblastoma, the most common pediatric liver cancer, is tightly linked to excessive Wnt/C/B?B=-catenin signaling. Microarray analysis identifitwo tumor subclasses resemb...
ORGANISM(S): Homo sapiens 
2008-12-19 | E-MEXP-1852 | biostudies-arrayexpress
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