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ProteomicsInherited mitochondrial dysfunction impacts corneal innervation fibre identity, fonctionnality and regenerative potential
The cornea is the transparent tissue covering the anterior part of the eye. Its main roles are to convey the light toward the retina, and to act as a protective barrier against infection or injury for the eye. The transparency of the cornea is a crucial component of its functionality and is the resu...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD052337 | Pride
Epithelium Mitochondria Transcriptomic Opa1 Innervation Proteomic Cornea Tear film 
ProteomicsTemporal analysis of tear fluid proteome reveals critical corneal repair events after photorefractive surgery
The cornea is the transparent tissue at the forefront of the eye. Its outermost layer, the corneal epithelium, acts as a protective barrier for the ocular chamber. The cornea is avascular and its homeostasis relies on alternative sources to receive nutrients and growth factors, essential for maintai...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD067691 | Pride
Tear film Epithelium Wound healing Proteomic Cornea 
ProteomicsComparative analysis of tear proteomics in PAX6 mutant and control mice of both sexes before and after abrasion
Our team is working on aniridia, an autosomal dominant condition and has used a mouse model. The cornea, the eye’s first avascular and transparent optical surface, is covered by a stratified epithelium that constantly renews itself; any disruption compromises transparency and threatens vision. The t...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-01 | PXD070553 | Pride
Tear proteomics Wound healing Pax6 Aniridia 
UnknownPostinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01.
Not available
S-EPMC3595424 | biostudies-literature
ProteomicsPLAPAX6: Proteomic study of tears from patients with a PAX6 mutation
The cornea is the eye’s first optical surface, avascular and transparent, covered externally by a stratified epithelium that constantly renews itself. Disruption in this renewal compromises transparency, potentially leading to vision loss. The corneal surface is protected and nourished by the tear f...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD066455 | Pride
Pax6 Aniridia Tears proteomic 
UnknownABCA7 rare variants and Alzheimer disease risk.
Not available
S-EPMC4898320 | biostudies-literature
ProteomicsDecoding the molecular complexity governing corneal wound closure in vivo
The cornea is the transparent tissue on the anterior surface of the eye. It is notably composed of a squamous stratified epithelium that forms a barrier protecting the ocular chamber. As the cornea is avascular, the delivery of nutrients and growth factors, required for corneal physiology, is essent...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD061492 | Pride
Epithelium Proteomics Cornea Lacrimal gland Epitranscriptomics Tears Transcriptomics 
UnknownAnalysis of the Contribution of Intrinsic Disorder in Shaping Potyvirus Genetic Diversity.
Not available
S-EPMC9504506 | biostudies-literature
TranscriptomicsMicroRNA sequencing and Novel HPV miRNA discovery in HPV cell lines and human tissue samples
Human papillomaviruses (HPV) preferentially infect keratinocytes of mucous membranes or skin and cause numerous benign and malignant lesions at different anatomical locations. A number of DNA viruses encode their own miRNAs as well. To date, no studies have been able to validate viral miRNAs in papi...
ORGANISM(S): Homo sapiens 
2013-08-18 | E-GEOD-42380 | biostudies-arrayexpress
UnknownVaccination perception and coverage among healthcare students in France in 2019.
Not available
S-EPMC7734903 | biostudies-literature
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