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ProteomicsTissue Microfibril Comparison - Structural and compositional diversity of fibrillin microfibrils in human tissues
Fibrillin microfibrils are large supramolecular ECM assemblies which play different functional roles in different tissues. We aim to compare the ultrastructure and biological composition of fibrillin microfibrils purified from human eye, skin and cultured dermal fibroblasts. This will allow us to un...
ORGANISM(S): Homo sapiens (Human) 
2018-02-16 | PXD008450 | Pride
Human Microfibril Afm Fibrillin Collagen Lc-ms/ms 
ProteomicsMass spectrometry detection of photodamage in human extracellular matrix assemblies
Photoageing in skin is commonly recognised by architectural remodelling of dermal extracellular matrix components. Mass spectrometry was previously used to identify tissue-specific patterns of fibrillin-1 and collagen VI peptide spectrum matches (PXD008450). This study aimed to determine if the same...
ORGANISM(S): Homo sapiens (Human) 
2020-01-30 | PXD015149 | Pride
Human Ecm Collagen vi Fibrillin Ultraviolet Microfibrils Lc-ms/ms 
ProteomicsProteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
Analysis of mouse Adamts6 and Adamts10 mutant embryos, lacking these homologous secreted metalloproteases individually and in combination, along with in vitro analysis of microfibrils, measurement of ADAMTS6-fibrillin affinities and N-terminomics determination of ADAMTS6-cleaved sites, demonstrates ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD027096 | Pride
Fibrillin Fibronectin Hek293t Adamts6 Extracellular matrix 
UnknownMultiscale Imaging Reveals the Hierarchical Organization of Fibrillin Microfibrils.
Not available
S-EPMC6193142 | biostudies-literature
UnknownElectric field bridging-effect in electrified microfibrils' scaffolds.
Not available
S-EPMC10634785 | biostudies-literature
UnknownComposite Gels Containing Whey Protein Fibrils and Bacterial Cellulose Microfibrils.
Not available
S-EPMC6593742 | biostudies-literature
UnknownFell-Muir Lecture: Fibrillin microfibrils: structural tensometers of elastic tissues?
Not available
S-EPMC5639267 | biostudies-literature
UnknownStructural and compositional diversity of fibrillin microfibrils in human tissues.
Not available
S-EPMC5892578 | biostudies-literature
UnknownExtracellular microfibrils: contextual platforms for TGFbeta and BMP signaling.
Not available
S-EPMC2767232 | biostudies-literature
UnknownNanoscale movements of cellulose microfibrils in primary cell walls.
Not available
S-EPMC5478883 | biostudies-literature
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