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ProteomicsDynamic protein phosphorylation in Streptococcus pyogenes during growth, stationary phase and starvation
The proteome and phosphoproteome of Streptococcus pyogenes M49 was investigated at different growth phases of cultures grown in either rich medium (THY), chemically defined medium without carbon source, or chemically defined medium containing 1% fructose. Of the 815 phosphosites identified, 463 were...
ORGANISM(S): Streptococcus pyogenes NZ131 Bacteria 
2024-05-22 | PXD044423 | Pride
Growth phases Phosphoproteome Label-free quantification Pasta kinase Streptococcus pyogenes m49 Proteome 
ProteomicsStoichiometry of two plant glycine decarboxylase complexes and comparison with a cyanobacterial glycine cleavage system
The multienzyme glycine cleavage system (GCS) converts glycine and tetrahydrofolate to the one-carbon compound 5,10-methylenetetrahydrofolate, which is of vital importance for most if not all organisms. Photorespiring plant mitochondria contain very high levels of GCS proteins organized as a fragile...
ORGANISM(S): Pisum sativum (Garden pea) Arabidopsis thaliana (Mouse-ear cress) 
2020-04-23 | PXD018211 | Pride
Arabidopsis Pea Quantification Stoichiometry Qconcat Glycine decarboxylase complex 
ProteomicsIntegrative analysis of multi-omics datasets for Synechocystis sp. PCC 6803 identifies novel elements in the salt acclimation process of cyanobacteria
The salt acclimation process of the euryhaline model cyanobacterium Synechocystis sp. PCC 6803 was analyzed by combining transcriptomic, proteomic and metabolomic methods. The comparison of salt-induced proteome and transcriptome changes revealed that most stably up-regulated proteins also showed el...
ORGANISM(S): Synechocystis sp. (strain PCC 6803 / Kazusa) 
2022-02-17 | PXD026118 | Pride
Hdmse Salt acclimation Label-free quantification Transcriptome-proteome correlation Synechocystis sp. pcc 6803 
ProteomicsLabel-free quantitative proteomic analysis of DNA methyltransferase mutants of the cyanobacterium Synechocystis sp. PCC 6803 – Analysis of the membrane-enriched fraction
Total protein and membrane-enriched fractions of Synechocystis sp. PCC 6803 wild type (WT) and mutant strains affected with inactivated DNA methyltransferase genes were analyzed by LC-HDMSE. The mutation of the DNA methyltransferase gene sll0729 encoding M.Ssp6803II initially led to a strong phenoty...
ORGANISM(S): Synechocystis sp. (strain PCC 6803 / Kazusa) 
2019-06-26 | PXD012698 | Pride
Dna methyltransferase Hdmse Label-free quantification Suppressor mutants Synechocystis sp. pcc 6803 
ProteomicsLabel-free quantitative proteomic analysis of DNA methyltransferase mutants of the cyanobacterium Synechocystis sp. PCC 6803 – Analysis of total protein extracts
Total protein and membrane-enriched fractions of Synechocystis sp. PCC 6803 wild type (WT) and mutant strains affected with inactivated DNA methyltransferase genes were analyzed by LC-HDMSE. The mutation of the DNA methyltransferase gene sll0729 encoding M.Ssp6803II initially led to a strong phenoty...
ORGANISM(S): Synechocystis sp. (strain PCC 6803 / Kazusa) 
2019-06-26 | PXD012751 | Pride
Dna methyltransferase Hdmse Label-free quantification Suppressor mutants Synechocystis sp. pcc 6803 
ProteomicsPeriodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome
Rheumatoid arthritis (RA) and periodontitis (PD) are chronic inflammatory diseases that appear to occur in tandem. Autoantibodies against citrullinated peptide antigens linked pathogeneses with PD preceding RA. However, the mutual impact PD exerts on RA and vice versa has not yet been defined. To ad...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-04 | PXD020397 | Pride
Collagen-induced arthritis Hdmse Mus musculus Rheumatoid arthritis Synovial membrane Periodontitis 
ProteomicsMemory-enhancing effects of Origanum majorana essential oil in an Alzheimer's amyloid beta1-42 rat model: a molecular and behavioral study
Origanum L. (Lamiaceae) is an important genus of medicinal and aromatic plants used in the traditional medicine since ancient times as culinary herbs and remedies. The effects of Origanum majorana-based aromatherapy was investigated in an Alzheimer's amyloid beta1-42 rat model. Protein extracts from...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-09-29 | PXD021082 | Pride
Alzheimer disease Rat Amyloid beta1-42 Brain tissue Origanum majorana 
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