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Metabolomics2E,4E-decadienoic acid, a novel anti-oomycete agent from co-culture of Bacillus subtilis and Trichoderma asperellum

Phytophthora nicotianae is an oomycete pathogen of global significance threatening many important crops. It is mainly controlled by chemosynthetic fungicides, which endangers ecosystem and human health; thus, there is an urgent need to explore alternatives for these fungicides. In this s...

2022-08-01 | MTBLS5405 | MetaboLights
MetabolomicsInvestigating the Impact of Acinetobacter lwoffii-ECT1/E6E7 Co-culture Metabolites on Cervical Cell Proliferation and Apoptosis via Untargeted Metabolomics.

This study employed untargeted metabolomics detection combined with bioinformatics analysis to investigate the metabolites from the co-culture of Acinetobacter lwoffiiand cervical precancerous cells ECT1/E6E7. A. lwoffiiwas co-cultured with ECT1/E6E7 cells at an MOI of 100. The culture supernatan...

2025-12-17 | MTBLS13526 | MetaboLights
ProteomicsDifferential regulation of proteins upon E-cadherin loss of function
In this project we undertook mass spectometry to measure differential expression of proteins using MDCK Wild Type (control) against MDCK E-cadherin Knock out
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2025-07-14 | PXD043091 | Pride
Emt Adherens junction Mdck E-cadherin 
ProteomicsIn vivo crosslinking, cell fractionation, immunoprecipitation and MS identification of proteins crosslinked to E. coli GapA-3xFLAG
Our BATCH assay suggested that glycolytic enzymes could associate into complexes of varied stoichiometry and potentially interact with proteins outside of glycolysis, moreover, PfkA, FbaA and GapA were the top interacting proteins, showing strong interactions with both the PTS and PNPase. We constru...
ORGANISM(S): Escherichia coli 
2026-07-16 | PXD068274 | Pride
Escherichia Ms Immunoprecipitation Crosslinking 
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
ProteomicsLigand binding and conformational dynamics of the E. coli nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry
Nicotinamide nucleotide transhydrogenases are integral membrane proteins that utilizes the proton motive force to reduce NADP+ to NADPH while converting NADH to NAD+. Atomic structures of various transhydrogenases in different ligand-bound states have become available, and it is clear that the molec...
ORGANISM(S): Escherichia coli 
2022-10-26 | PXD037413 | Pride
Channel opening Membrane protein Small ligand binding Hdx-ms Cyclic ims‑ms 
ProteomicsProteomes of E. coli W3110 samples grown in different growth media
This dataset contains E. coli W3110 samples grown in different growth conditions and harvested at different growth stages. A mapping between conditions and files is contained in the SDRF. This dataset is one of 40 projects included in the E. coli PanProteome PeptideAtlas build:Escherichia coli is a ...
ORGANISM(S): Escherichia coli 
2025-09-18 | PXD058808 | Pride
Growth medium Growth phase E.coli Lc-ms/ms 
MetabolomicsAnalysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors

Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and adults in endemic areas. Gene regulation of ETEC during growth in vitro and in vivo needs to be further evaluated, and here we describe the full transcriptome and metabolome of ETEC dur...

2022-07-15 | MTBLS3540 | MetaboLights
ProteomicsQuantitative phosphoproteomics of drought-stressed Arabidopsis thaliana Col-0 wild type as well as mutants of Clade E and Clade A (Highly ABA-Induced 1) protein phosphatase 2Cs.
I-Traq based quantitative phosphoproteomics was used to examine changes in phosphopeptide abundance over longer term drought (low water potential) treatments. Samples were analyzed from unstressed seedlings grown on agar plates and from seedlings of the same age that had been transferred to low wat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-01-17 | PXD004869 | Pride
Arabidopsis Tio2 Phosphoproteomics Hai1 Protein phosphatase 2cs Itraq Drought 
MetabolomicsDistinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones

INTRODUCTION: Prostatitis is likely to occur in younger or middle-aged men, while prostate cancer is likely to occur in older men. Although amino acids and lipids as biomarkers of prostate cancer have been examined using prostate cancer cell lines/tissues, no previous studies hav...

2020-11-04 | MTBLS2028 | MetaboLights
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