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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
ProteomicsIn vivo protein interaction network analysis reveals porin-localized toxin inactivation in antibiotic resistant bacteria
The nosocomial pathogen Acinetobacter baumannii is a frequent cause of hospital acquired infections worldwide, and a challenge for treatment due to its evolved resistance to antibiotics, including carbapenems. To gain insight on A. baumannii antibiotic resistance mechanisms, we analyzed the protein...
ORGANISM(S): Acinetobacter baumannii AB5075 
2016-12-22 | PXD004236 | Pride
Acinetobacter baumannii Chemical cross-linking Protein-protein interactions Antibiotic resistance Carbapenem 
UnknownThe cell line A-to-I RNA editing catalogue.
Not available
S-EPMC7293008 | biostudies-literature
UnknownPerformance-based assessment of social skills in a large sample of participants with schizophrenia, bipolar disorder and healthy controls: Correlates of social competence and social appropriateness.
Not available
S-EPMC10857848 | biostudies-literature
UnknownToll-like receptor 2 (TLR2)-deficiency impairs male mouse recovery from a depression-like state.
Not available
S-EPMC7572513 | biostudies-literature
UnknownAn enzyme linked immunosorbent assay (ELISA) for the determination of the human haptoglobin phenotype.
Not available
S-EPMC3717392 | biostudies-literature
UnknownGlobal quantification exposes abundant low-level off-target activity by base editors.
Not available
S-EPMC8647836 | biostudies-literature
MetabolomicsDivergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies. The complex metabolic relationships that exist between members of the intestinal m...
2017-03-03 | MTBLS422 | MetaboLights
UnknownInflammatory markers are associated with decreased psychomotor speed in patients with major depressive disorder.
Not available
S-EPMC4939278 | biostudies-literature
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