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UnknownOccult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial.
Not available
S-EPMC3221530 | biostudies-literature
UnknownEffect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC4979167 | biostudies-literature
TranscriptomicsInnervated and 2 month Denervated Rat EDL muscles
The right legs of 8 Brown-Norway male rats were denervated by a high sciatic nerve section in the hip region of the hind limb.Two months after denervation (6 months of age), extensor digitorum longus (EDL) muscles were removed from the operated legs. The EDL muscles from 8 age-matched non-operated r...
ORGANISM(S): Rattus norvegicus 
2004-09-10 | E-GEOD-1741 | biostudies-arrayexpress
ProteomicsRNA-binding proteins associating with the 3’UTR of the ATP6V1A transcript in SIRT1 knock-down cells
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) binds various RNA transcripts and functions as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism (1-3). Here we find that IGF2BP2 binds to the 3’ untranslated region of the tran...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028114 | Pride
Breast cancer Sirt1 Rna-binding proteins Human Atp6v1a 
ProteomicsThe interactome of Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2)
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) binds various RNA transcripts and functions as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism (1-3). Here we find that IGF2BP2 binds to the 3’ untranslated region of the tran...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028084 | Pride
Sirt1 Igf2bp2 Protein-protein interactions 
UnknownAcid, silver, and solvent-free gold-catalyzed hydrophenoxylation of internal alkynes.
Not available
S-EPMC3817533 | biostudies-literature
TranscriptomicsTranscription profiling of human B-cell lymphoma cell lines treated with motexafin gadolinium and zinc reveals induced oxidative stress responses and apoptosis
There is an emerging appreciation of the importance of zinc in regulating cancer cell growth and proliferation. Recently, we showed that the anticancer agent motexafin gadolinium (MGd) disrupted zinc metabolism in A549 lung cancer cells, leading, in the presence of exogenous zinc, to cell death. Her...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2964 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the proteins co-purified with FLAG-HA Non-Stop FLAG-IPed from Drosophila melanogaster S2 cells
Protein Complexes Purification- Drosophila S2 cells were stably-transfected with pRmHa3-based inducible expression vectors to produce epitope-tagged Non-stop-2xFLAG-2xHA (Non-stop-FH). Cells stably transfected with empty vector served as negative control. Protein complexes containing Non-stop were p...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2018-07-17 | MSV000082625 | MassIVE
TranscriptomicsRNA-seq from heart tissue of 192 heterogeneous stock rats
We measured heart gene expression in 192 heterogeneous stock rats. These animals were part of a larger cohort that were extensively phenotyped and genotyped and originally published in PMID: 23708188, although the gene expression data here were not included in that study.
ORGANISM(S): Rattus norvegicus 
2023-04-03 | E-MTAB-12701 | biostudies-arrayexpress
ProteomicsAcarbose improves late-life physical function in mice of both sexes, but rejuvenates cardiac structure and lipid profile in males only
With an expanding aging population burdened with comorbidities, there is considerable interest in treatments that optimize health in later life. Acarbose (ACA), a drug used clinically to treat Type 2 diabetes (T2DM) can extend mouse lifespan, with greater effect in males than in females. Utilizing a...
ORGANISM(S): Mus Musculus 
2021-03-03 | PXD017706 | panorama
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