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TranscriptomicsTranscription profiling of rat cardiac myocytes and fibroblasts subjected to 24 hours of mechanical stress, or treated with a single dose of ionizing or ultraviolet radiation and allowed to recover for 24 hours
Rationale: During excessive pressure or overload, cardiac cells are subjected to increased mechanical stress. We investigate how the stress response of cardiac cells to mechanical stress can be compared to genotoxic stresses induced by DNA damaging agents. Methods: Cultures enriched for cardiomyocyt...
ORGANISM(S): Rattus norvegicus 
2007-09-18 | E-GEOD-2032 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human polymorphonuclear leukocytes (PMNs) from healthy individuals vs patients with X-linked chronic granulomatous disease
Polymorphonuclear leukocytes (PMNs) were obtained from healthy individuals (Healthy1, Healthy2, Healthy3, and Healthy4) or patients with X-linked chronic granulomatous disease (XCGD1, XCGD2, XCGD3, XCGD4, XCGD5, and XCGD6). The studies were performed in accordance with a protocol approved by the Ins...
ORGANISM(S): Homo sapiens 
2007-09-29 | E-GEOD-935 | biostudies-arrayexpress
UnknownImpact of age and renal function on urine chemistry in patients with calcium oxalate kidney stones.
Not available
S-EPMC8361852 | biostudies-literature
UnknownThe structure of the MAP2K MEK6 reveals an autoinhibitory dimer.
Not available
S-EPMC3689539 | biostudies-literature
TranscriptomicsGBM-Space: Spatial Transcriptomic Profiling of Glioblastoma (10x Genomics - Visium)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17164 | biostudies-arrayexpress
UnknownA Comparison of Time Delay in Three Continuous Glucose Monitors for Adolescents and Adults.
Not available
S-EPMC5951038 | biostudies-literature
UnknownEffectiveness of music with auditory beat stimulation in reducing state anxiety in Canadian students with trait anxiety: protocol for a randomised controlled trial.
Not available
S-EPMC12182183 | biostudies-literature
UnknownCRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells.
Not available
S-EPMC6402849 | biostudies-literature
ProteomicsInduction of the immunoproteasome subunit Lmp7 links proteostasis and immunity in α-synuclein aggregation disorders, part 1
Accumulation of aggregated α-synuclein into Lewy bodies is thought to contribute to the onset and progression of dopaminergic neuron degeneration in Parkinson’s disease (PD) and related disorders. Although protein aggregation is associated with perturbation of proteostasis, how α-synuclein aggregat...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-18 | PXD009717 | Pride
Phosphoproteome Immunoproteasome Α-synuclein Proteomoe 
ProteomicsInduction of the immunoproteasome subunit Lmp7 links proteostasis and immunity in α-synuclein aggregation disorders, part 2
Accumulation of aggregated α-synuclein into Lewy bodies is thought to contribute to the onset and progression of dopaminergic neuron degeneration in Parkinson’s disease (PD) and related disorders. Although protein aggregation is associated with perturbation of proteostasis, how α-synuclein aggregat...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-18 | PXD009718 | Pride
Proteomics Immunoproteasome Phosphoproteomics Α-synuclein 
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