Sort   by:  
 Page size 
MetabolomicsMetabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
The blood-feeding behavior of Anopheles females delivers essential nutrients for egg development and drives parasite transmission between humans. Plasmodium growth is adapted to the vector reproductive cycle, but how changes in the reproductive cycle impact parasite development remains unclear. Here...
2021-11-03 | MTBLS1282 | MetaboLights
MetabolomicsCancer-cell-secreted exosomal miR-105 promotes tumour growth through the Myc-dependent metabolic reprogramming of stromal cells
Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and to buffer the negative effects of environmental changes. Extracellular miRNAs have been recently implicated in the intercellular crosstalk. Here we show a mechanistic model involving breast-canc...
2018-07-10 | MTBLS626 | MetaboLights
MetabolomicsUntargeted metabolomics of miR-142 WT vs KO CML cells
Not available
ORGANISM(S): Mus musculus 
ST002446 | MetabolomicsWorkbench
MetabolomicsmiR-9394b from Lactobacillus paracasei extracellular vesicles targets iNOS to reprogram host NO-ornithine metabolism and ameliorate ulcerative colitis

Background Probiotics have attracted considerable interest for ulcerative colitis (UC); however, their efficacy is highly strain-specific and the underlying molecular mechanisms remain incompletely understood.

Results Accumulating evidence indicates that bacterial extracellular vesicles (BE...

2026-01-23 | MTBLS13753 | MetaboLights
MetabolomicsExercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway

OBJECTIVE: To explore the cardioprotective effects of exercise-derived β-aminoisobutyric (BAIBA) on cardiomyocyte apoptosis and energy metabolism in a rat model of heart failure (HF).

METHODS: In male Sprague-Dawley rats (8-week-old), myocardial infarction ...

2022-03-08 | MTBLS3927 | MetaboLights
ProteomicsMulti-Pathway Regulatory role of miR-4693-5p in Rheumatoid Arthritis
This study investigated the downstream effects of miR-4693-5p on key proteins and pathways associated with RA.
ORGANISM(S): Homo sapiens (Human) 
2025-10-29 | PXD069734 | Pride
Synovial fibroblast Swath-ms Rheumatoid arthritis Mir-4693-5p 
Proteomics,MultiomicsmiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signaling in human colorectal adenocarcinoma cells
Oxaliplatin (oxPt) resistance in colorectal cancers (CRC) is a major unsolved problem. Consequently, predictive markers and a better understanding of resistance mechanisms are urgently needed. To investigate if the recently identified predictive miR-625-3p is functionally involved in oxPt resistance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080762 | MassIVE
TranscriptomicsIdentification of dysregulated genes after deletion of miR-1-1 and miR-1-2
Purpose: The goals of this study are to identify dysregulated mRNAs in the heart after deletion of miR-1-1 and miR-1-2. Methods: Total RNAs were extracted from hearts at embryonic E15.5 (E15.5) or postnatal 2.5 days (P2.5) of miR-1s dHET and miR-1s dKO mice. mRNAs were purified using a poly-A selec...
ORGANISM(S): Mus musculus 
2014-03-26 | E-GEOD-45760 | biostudies-arrayexpress
ProteomicsThe transcription factor TAL1 and the miR-17-92 cluster establish a regulatory loop
A network of gene regulatory factors such as transcription factors and microRNAs establish and maintain the gene expression pattern during hematopoiesis. In this network transcription factors regulate each other and are involved in regulatory loops with microRNAs.The microRNA cluster miR-17-92 is lo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018052 | Pride
Human Microrna Blood Tal1 Jurkat cells Mir-17-92 Hematopoiesis 
Transcriptomicshsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq]
We constructed a genome wide target profile of hsa-miR-503, hsa-miR-103, and hsa-miR-494 by sequencing RNA isolated from Ago2 immunoprecipitations and total RNA samples following transfection of the respective miRNA in mature duplex form Examination of mRNA levels in HeLa cells and Ago2 immunoprecip...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-64615 | biostudies-arrayexpress
Sort   by:  
 Page size