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ProteomicsHuman MDA-MB-231 breast cancer cells overexpressing miR-183-5p and its isomiRs
Overexpression of miR-183-5p|+2, but not of the other two isomiRs |0 and |+1, was observed to reduce cell cycle and cell proliferation in different triple-negative breast cancer cell lines. Therefore, we hypothesized that the |+2 isoform has targets distinct from the other two isoforms. To test this...
ORGANISM(S): Homo sapiens (Human) 
2022-05-26 | PXD026763 | Pride
Human Breast cancer Mir-183-5p Mirna Mda-mb-231 
GenomicsGene expression profile of cholangiocarcinoma（CCA）cells by overexpressing miR-182/183-5p
Gene expression profile of cholangiocarcinoma（CCA）cells by overexpressing miR-182/183-5p
PRJNA884270 | ENA
TranscriptomicsGene expression profile of cholangiocarcinoma（CCA）cells by overexpressing miR-182/183-5p
Cholangiocarcinoma (CCA) is a type of highly aggressive cancer arising from the biliary system. Through miRNA sequencing, we screened that miR-182/183-5p was highly expressed in bile exosomes. miRNA affects gene expression by binding to mRNA or otehr. Here we profile the transcriptome of CCA cells f...
ORGANISM(S): Homo sapiens 
2025-09-26 | GSE214159 | GEO
UnknownmiR-183-5p Aggravates Breast Cancer Development via Mediation of RGS2.
Not available
S-EPMC8627563 | biostudies-literature
UnknownmiR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons.
Not available
S-EPMC5849806 | biostudies-literature
UnknownlncRNA LINC00960 promotes apoptosis by sponging ubiquitin ligase Nrdp1-targeting miR-183-5p.
Not available
S-EPMC10157604 | biostudies-literature
UnknownMiR-183-5p promotes migration and invasion of prostate cancer by targeting TET1.
Not available
S-EPMC10334645 | biostudies-literature
UnknownExosomal miR-183-5p promotes angiogenesis in colorectal cancer by regulation of FOXO1.
Not available
S-EPMC7244076 | biostudies-literature
UnknownStriatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling.
Not available
S-EPMC9549132 | biostudies-literature
TranscriptomicsBeyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
The product of genomic loci coding for micro RNAs (miRNAs) produce many isoforms (isomiRs). IsomiRs differing at their 5’ end have different seed regions and therefore are expected to target different genes. We used microarrays to study the effect of different isomiRs in the context of breast cancer...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-71950 | biostudies-arrayexpress
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