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To investigate differences in gene expression after overexpression miR-218 in U251MG 2 Samples, one transduced with miR-control and one with miR-218.
ORGANISM(S): Homo sapiens 
Receptor tyrosine kinase pathway signalings plays a central role in the growth and progression of glioblastoma, a highly aggressive group of brain tumors. We recently reported that miR-218 repression, an essentially uniform feature of human GBM, directly promotes RTK hyperactivation by increasing th...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD002112 | Pride
The involvement of motor neuron specific miR-218 in human ALS
Genomics
miR-218
Motor-neuron specific microRNA-218 (miR-218) was recently put in the spotlight because of its striking roles in mouse development. However, miR-218 relevance to human motor neuron disease was not yet explored. Here, we demonstrate by neuropathology that miR-218 is abundant in healthy human motor neu...
ORGANISM(S): Mus musculus 
2019-08-28 | GSE136409 | GEO
Noncoding RNAs, especially microRNAs (miRNAs) have been implicated in the regulation of neuronal functions, such as learning, cognition and memory formation. However, the particular miRNAs involved in drug-induced behavioral plasticity are largely unknown. Here we report a novel regulator, miR-218, ...
ORGANISM(S): Rattus norvegicus synthetic construct 
2017-03-08 | GSE89202 | GEO
A hidden threshold in motor neuron gene networks for survival revealed by modulation of miR-218 dose
Differentially Expressed Genes in C-33A and CaSki Cells Overexpressing miR-124-3p, miR-23b-3p, or miR-218-5p Modulate Processes and Pathways Involved in Cervical Cancer Progression
To investigate differences in gene expression after overexpression miR-218 in U251MG
ORGANISM(S): Homo sapiens 
2013-04-19 | GSE46059 | GEO
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