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ProteomicsMouse Articular chondrocyte LC-MSMS of wild-type, miR-26a -/- and cartilage-specific miR-23ab clusters knockout mice
To reveal the potential regulation target genes of miR-26a and miR-23a/b clusters in articular chondrocytes, we performed a multi-omics analysis of LC-MSMS and RNA-seq using cultured chondrocytes samples, which were primarily isolated from 3-week-old wild-type, miR-26a -/- (with or without miR-26a m...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-25 | PXD031868 | Pride
Lc-msms Chondrocyte Mouse Mir-26a Mir-23 cluster 
TranscriptomicsTrastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
Objective: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC ...
ORGANISM(S): Homo sapiens 
2012-06-02 | E-GEOD-38415 | biostudies-arrayexpress
ProteomicsIn-depth analysis of miRNA binding sites reveals the complex response of uterine epithelium to miR-26a-5p and miR-125b-5p during early pregnancy
Post-transcriptional regulation of gene expression by miRNAs likely makes significant contributions to mRNA abundance at the embryo-maternal interface. In this study, we investigated how miR-26a-5p and miR-125b-5p contribute to molecular changes occurring in the uterine luminal epithelium, which ser...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-07 | PXD056243 | Pride
Mirna-mrna interactions Pregnancy De novo protein synthesis Uterine luminal epithelium Pulsed silac 
TranscriptomicsRNA-sequencing (RNA-seq) in breast cancer cell lines after ectopic manipulation of miR-26a expression
RNA sequencing technology has been carried out in order to evaluate mRNA expression changes after manipulation of miR-26a in both MCF-7 and MDA-MB-231 breast cancer cell lines. To evaluate the entire set of genes modulated by miR-26a in breast cancer, we performed RNA-seq after ectopic manipulation ...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-43726 | biostudies-arrayexpress
GenomicsMiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages
MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages
PRJNA630260 | ENA
GenomicsRNA Sequencing Analyzes Chondrocyte Transcriptomes of Wild-type, miR-26a -/- and Cartilage-specific miR-23a/b clusters Knockout Mice
RNA Sequencing Analyzes Chondrocyte Transcriptomes of Wild-type, miR-26a -/- and Cartilage-specific miR-23a/b clusters Knockout Mice
PRJNA810025 | ENA
TranscriptomicsDiscovering the miR-26a/targetome in prostate cancer cells
In this work, we showed that the re-expression of miR-26a in DU-145 prostate cancer cells restored the tumor suppressor activity of miR-26a. To discover the genes and pathways elicited by miR-26a re-expression, we used the miRNA pull out assay to capture and the Next Generation Sequencing to identif...
ORGANISM(S): Homo sapiens 
2017-04-04 | GSE85306 | GEO
GenomicsGene expression of CTCL cell line MyLa transduced with Empty-GFP or miR-26a-GFP expressing vector
Gene expression of CTCL cell line MyLa transduced with Empty-GFP or miR-26a-GFP expressing vector
PRJNA748376 | ENA
GenomicsDifferentially expressed genes in HTR-8/SVneo cell overexpressing miR-26a-5p modulate invasion and migration
Differentially expressed genes in HTR-8/SVneo cell overexpressing miR-26a-5p modulate invasion and migration
PRJNA1266212 | ENA
TranscriptomicsTranscription profiling by array of hMADS cells transfected with miR-26a
Human multipotent adipose-derived stem (hMADS) cells were transfected at confluence with miR-26a or miR-C (non-targeting control microRNA) and cells were harvested two days later (=d0) to identify mRNAs that are downregulated by miR-26a versus miR-C, as such mRNAs could be direct miR-26a targets.
ORGANISM(S): Homo sapiens 
2013-11-25 | E-MARS-28 | biostudies-arrayexpress
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