To gain better insight into the molecular link between the post-mating transcriptional and morphological changes and the behavioral and physiological shift induced by copulation in An. gambiae females, we performed an in-depth transcriptional analysis of the female lower reproductive tract (LRT), co...
Male Anophele gambiae mosquitoes transfer the steroid hormone 20-hydroxyecdysone (20E) to the female lower reproductive tract during mating. We have shown that this sexually transferred hormone is a key regulator of monandry and oviposition in An. gambiae females. In order to identify possible molec...
To gain insight into the molecular pathways and processes controlling the behavioral and physiological shift induced by copulation in An. gambiae, we performed an in-depth transcriptional analysis of the heads of mated females. We analyzed three time points post-mating (3, 12 and 24 hours post matin...
Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as cell scattering and invasion. The endosomal system influences how RTK sign...
Since Anopheles gambiae female mosquitoes mate only once in their lifetime, and store sperm received from males potentially for weeks, genes and pathways regulated by mating in the sperm storage organ (spermatheca) to preserve sperm function may represent new targets for vector control. The transcri...
Transcriptome profiling of a multi insecticide resistant strain of Anopheles gambiae from Burkina Faso compared to a susceptible strain Ngousso from Cameroon.
