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ProteomicsTreating the placenta with nanoparticles to prevent altered placental secretion and fetal development in response to hypoxia [Conditioned Medium]
Hypoxia-related pregnancy complications increase the risk of disease in the child in later life. No prevention is available. Previously we noted that a trophoblast barrier, an in vitro model of the placenta, reacted to oxidative stress by secreting factors that damage neighbouring cells. Application...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-08-22 | PXD004956 | Pride
Pregnancy Placenta Oxidative stress Mitoq Fetal development Nanoparticles Hypoxia 
GenomicsSearch for biomarkers of response to MitoQ in human breast cancer cell lines
Search for biomarkers of response to MitoQ in human breast cancer cell lines
PRJNA623273 | ENA
ProteomicsTreating the placenta with nanoparticles to prevent altered placental secretion and fetal development in response to hypoxia [Fetal Plasma]
Hypoxia-related pregnancy complications increase the risk of disease in the child in later life. No prevention is available. Previously we noted that a trophoblast barrier, an in vitro model of the placenta, reacted to oxidative stress by secreting factors that damage neighbouring cells. Application...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-08-22 | PXD004955 | Pride
Oxidative stress Placenta Mitoq Fetal development Blood Pregnancy Plasma Hypoxia Nanoparticles 
ProteomicsTargeting mitochondrial reactive oxygen species alleviates allergic airway disease in a mouse model of obese allergic asthma
Obesity is associated with severe, difficult to control asthma, and increased airway oxidative stress. Mitochondrial reactive oxygen species (mROS) are an important source of oxidative stress leading us to hypothesize that targeting mROS in obese allergic asthma might be an effective treatment strat...
ORGANISM(S): Bos taurus (Bovine) Mus musculus (Mouse) 
2023-06-02 | PXD029715 | Pride
Obesity Mitochondrial reactive oxygen species (mros) Allergic asthma Airway oxidome Unfolded protein response (upr). Mitoquinone Tissue eosinophilia 
UnknownMitoQ Is Able to Modulate Apoptosis and Inflammation.
Not available
S-EPMC8124358 | biostudies-literature
UnknownMitoquinone (MitoQ) Inhibits Platelet Activation Steps by Reducing ROS Levels.
Not available
S-EPMC7503844 | biostudies-literature
UnknownMitoQ Protects Against Oxidative Stress-Induced Mitochondrial Dysregulation in Human Cardiomyocytes.
Not available
S-EPMC12271626 | biostudies-literature
ProteomicsOXPHOS TARGETING OF MYCN-AMPLIFIED NEUROBLASTOMA
High risk - neuroblastoma (HR-NB) is a pediatric solid tumor with high lethality. Half of HR-NB are driven by MYCN gene amplification (MNA). These HR-NBs require high dosage chemotherapy and often relapse. Moreover, current therapies can cause severe long-term side effects and new therapies are urge...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD069621 | Pride
Neuroblastoma Dpi Mitoq Childhood cancer Combination therapy Metabolism. Oxidative stress 
UnknownMitoQ regulates autophagy by inducing a pseudo-mitochondrial membrane potential.
Not available
S-EPMC5388232 | biostudies-literature
UnknownMitochondria-targeted antioxidant MitoQ radiosensitizes tumors by decreasing mitochondrial oxygen consumption.
Not available
S-EPMC11681259 | biostudies-literature
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