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This model represents the main aspects of regulation of mitotic exit in budding yeast, including the MEN and FEAR network. As a compartmental model, it represents spatial aspects of regulation alongside regulation of enzymatic activity.
2020-11-26 | MODEL2007200001 | BioModels
In budding yeast, the Mitotic Exit Network (MEN), a GTPase signaling cascade integrates spatial and temporal signals to promote exit from mitosis. This signal integration requires transmission of a signal created on the cytoplasmic face of the spindle pole bodies (SPBs, functional equivalent of the ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-01-14 | PXD020369 | Pride
Mathematical model of mitotic exit in budding yeast.
2024-09-02 | BIOMD0000000953 | BioModels
Mitotic bookmarking transcription factors (TFs) are thought to mediate rapid and accurate post-mitotic gene reactivation. However, the loss of individual bookmarking TFs often leads to the deregulation of only a small proportion of their mitotic targets, raising doubts on the significance and import...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-20 | PXD038950 | Pride
Candida albicans demonstrates three main growth morphologies yeast, pseudohyphal and true hyphal forms. Cell separation is distinct in these morphological forms and the process of separation is closely linked to the completion of mitosis and cytokinesis. In Saccharomyces cerevisiae the small GTPas...
ORGANISM(S): Candida albicans 
This model is from the article: Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Queralt E, Lehane C, Novak B, Uhlmann F. Cell. 2006 May 19;125(4):719-32. 16713564 , ...
2024-09-02 | BIOMD0000000409 | BioModels
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