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ProteomicsPolQ peptide 4S-P (1482-P/86-P/88-P/93-P) binding partners identification
We characterized residus of PolQ which are phosphorylated during mitotis. We aimed to identify the partners of the phosphorylated residus of PolQ.
ORGANISM(S): Homo sapiens (Human) 
2023-09-18 | PXD042167 | Pride
Polq Phosphorylation 
TranscriptomicsAGO4 Regulates Entry into Meiosis and Influences Silencing of Sex Chromosomes in the Male Mouse Germline
The four mammalian Argonaute family members are thought to share redundant functions in the microRNA pathway, yet only AGO2 possesses the catalytic "slicer" function required for RNA interference. Whether AGO1, AGO3, or AGO4 possess specialized functions remains unclear. Here, we Series_su...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-39652 | biostudies-arrayexpress
GenomicsOctameric nucleosomes are present within the inner kinetochore of human centromeres
The centromere is a vital locus on each chromosome which seeds the kinetochore, allowing for a physical connection between the chromosome and the mitotic spindle. At the heart of the centromere is the centromere-specific histone H3 variant CENP-A/CENH3. Throughout the cell cycle the constitutive cen...
ORGANISM(S): Homo sapiens 
2020-04-02 | GSE129351 | GEO
UnknownPARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.
Not available
S-EPMC5325429 | biostudies-literature
GenomicsTopoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1 [SLAM-seq]
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1 [SLAM-seq]
PRJNA718531 | ENA
UnknownProbing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes.
Not available
S-EPMC3005937 | biostudies-literature
ProteomicsOrdered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit
APC/C-mediated proteolysis of cyclin B and securin promotes entry into anaphase, inactivating CDK1 and permitting chromosome segregation, respectively. Reduction of CDK1 activity relieves inhibition of the CDK1-opposing phosphatases PP1 and PP2A-B55 leading to dephosphorylation of substrates crucial...
ORGANISM(S): Homo sapiens (Human) 
2020-09-04 | PXD019787 | Pride
Dephosphorylation Mitotis Mitotic exit Cell cycle Apc/c 
GenomicsOctameric nucleosomes are present within the inner kinetochore of human centromeres
Octameric nucleosomes are present within the inner kinetochore of human centromeres
PRJNA531000 | ENA
TranscriptomicsGenome-wide gene expression in response to mating pheromones in S. pombe
Fission yeast cells undergo sexual differentiation in response to nitrogen starvation. In this process haploid M and P cells first mate to form diploid zygotes, which subsequently enter meiosis and sporulate. Prior to mating, M cells secrete M-factor and P-cells secrete P-factor, and these diffusibl...
ORGANISM(S): Schizosaccharomyces pombe 
2007-08-21 | E-GEOD-5323 | biostudies-arrayexpress
TranscriptomicsTranscription factor NFYA directs male meiotic entry by regulating accessible chromatin at meiotic promoters in mice
Meiotic prophase I characterized by homologous recombination and synapsis is an intricate step for spermatogenesis. This process entails extensive changes to chromatin and transcription. Recent studies have revealed that prior to prophase I, accessible chromatin bound by paused Pol II at meiotic gen...
ORGANISM(S): Mus musculus 
2025-11-20 | E-MTAB-16210 | biostudies-arrayexpress
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