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ProteomicsProteomic analysis of MNT-1 cells deficient in NPC1 protein
A novel MNT-1 cell line deficient in NPC1 protein was generated using CRISPR/CAS9 knock-out method. In the absence of the NPC1 protein the pigmentation status of the cells was changed and alterations in the melanogenesis process were observed. In order to characterize the role of NPC1 protein in the...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD042762 | Pride
Melanogenesis Npc1 protein Proteome Mnt-1 
GenomicsMYC-MNT-MAX
The MYC antagonist MNT autoregulates its expression and supports proliferation in MAX deficient cells
PRJEB23604 | ENA
TranscriptomicsExpression data from skeletal muscles of flies with muscle-specific overexpression of Foxo or Mnt
Skeletal muscle senescence influences whole organism aging, yet little is known on the relay of pro-longevity signals from muscles to other tissues. We performed an RNAi screen in Drosophila for muscle-released cytokines ('myokines') regulating lifespan and identified Myoglianin, the homolog of huma...
ORGANISM(S): Drosophila melanogaster 
2014-07-02 | E-GEOD-39877 | biostudies-arrayexpress
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Proteomes 2
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037147 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Proteomes 1
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037146 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Exosomes
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037149 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
UnknownMNT and Emerging Concepts of MNT-MYC Antagonism.
Not available
S-EPMC5333072 | biostudies-literature
UnknownMnt modulates Myc-driven lymphomagenesis.
Not available
S-EPMC5686348 | biostudies-literature
UnknownMNT: a new target for AML.
Not available
S-EPMC12549552 | biostudies-literature
TranscriptomicsAnalysis of melanosomal miRNAs
miRNA microarray profiling was performed for MNT-1 cells, pre-mature and mature melanosomes extracted from MNT-1 cells. In order to reveal the miRNAs that are most abundant in mature melanosomes, the most highly expressed miRNAs from mature melanosomes were compared with expression levels in pre-mat...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-72337 | biostudies-arrayexpress
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