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ProteomicsProteomic analysis of MNT-1 cells deficient in NPC1 protein
A novel MNT-1 cell line deficient in NPC1 protein was generated using CRISPR/CAS9 knock-out method. In the absence of the NPC1 protein the pigmentation status of the cells was changed and alterations in the melanogenesis process were observed. In order to characterize the role of NPC1 protein in the...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD042762 | Pride
Melanogenesis Npc1 protein Proteome Mnt-1 
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Proteomes 1
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037146 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Proteomes 2
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037147 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
ProteomicsHuman - Cells and Extracellular vesicles of Hela and MNT-1 WT vs CD63 KO Exosomes
CD63 is a tetraspanin, which organize on cholesterol enriched microdomains, especially on late endosomes. Previous work of our team has shown that CD63 could regulate the sorting of cargoes into ILVs through an ESCRT-independent manner in melanocytes. However, CD63 has also been involved in other tr...
ORGANISM(S): Homo sapiens (Human) 
2024-04-19 | PXD037149 | Pride
Cd63 Extracellular vesicles (ev) Hela Mnt-1 Cell lines 
GenomicsNext Generation Sequencing facilitates the identification of differential gene expression between MNT-1 expressing control or shABCB6.
Next Generation Sequencing facilitates the identification of differential gene expression between MNT-1 expressing control or shABCB6.
PRJNA707000 | ENA
TranscriptomicsAnalysis of melanosomal miRNAs
miRNA microarray profiling was performed for MNT-1 cells, pre-mature and mature melanosomes extracted from MNT-1 cells. In order to reveal the miRNAs that are most abundant in mature melanosomes, the most highly expressed miRNAs from mature melanosomes were compared with expression levels in pre-mat...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-72337 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression analysis of MNT-1 cell under hyperosmotic condition
In order to investigate the effect of hyperosmotic stress on melanoma cell line, we performed a gene expression microarray analysis from RNAs isolated from MNT-1 cells treated by sucrose or not
ORGANISM(S): Homo sapiens 
2014-12-31 | GSE57565 | GEO
TranscriptomicsNext Generation Sequencing facilitates the identification of differential gene expression between MNT-1 expressing control or shABCB6.
The goal of this study is to investigate the effect of ABCB6 inhibition on the transcriptome level of melanoma cell line MNT-1. We performed next-generation sequencing (NGS) on both ABCB6 depleted MNT-1 cells (shABCB6) and unknocked control cells (CTRL). Illumina mRNA-seq sample preparation kit was ...
ORGANISM(S): Homo sapiens 
2021-03-06 | GSE168345 | GEO
TranscriptomicsAnalysis of melanosomal, exosomal and cellular miRNAs of melanoma cells
miRNA microarray profiling was performed for exosomes and secreted melanosomes of MNT-1 cells as well as WM3682 and WM3314 cells and melanosomes isolated from cell homogenates. The aim of this study is to compare the miRNA content of exosomes and secreted melanosomes and to assess differences in the...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-79411 | biostudies-arrayexpress
GenomicsHomo sapiens
Genome-wide gene expression analysis of MNT-1 cell under hyperosmotic condition
PRJNA246709 | ENA
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