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UnknownA whole-food, plant-based intensive lifestyle intervention improves glycaemic control and reduces medications in individuals with type 2 diabetes: a randomised controlled trial.
Not available
S-EPMC11732952 | biostudies-literature
ProteomicsImmunoseroproteomic profiling in prostate cancer
Mass spectrometry analysis of immunoreactive protein spots revealed that seveal prostate cancer patient sera had autoantibodies to a number of proteins associated with both the glycolysis and plasminogen pathways.
ORGANISM(S): Homo sapiens (Human) 
2017-01-06 | PXD003968 | Pride
Glycoslysis Autoantibodies Tumor-associated antigens Prostate cancer Plasminogen 
UnknownInhaled nitrite reverses hemolysis-induced pulmonary vasoconstriction in newborn lambs without blood participation.
Not available
S-EPMC3077283 | biostudies-literature
TranscriptomicsZic3 ChIP-on-chip in mouse ES cells
The transcription factor Zic3 is required for maintenance of embryonic stem (ES) cell pluripotency (Lim LS et al, Mol Biol Cell. 2007;18:1348-1358). By genome-wide chromatin immunoprecipitation (ChIP-chip) in ES cells, we have identified 379 direct Zic3 targets, many of which are functionally associ...
ORGANISM(S): Mus musculus 
2010-09-13 | E-GEOD-22195 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fetal lung epithelial cells in undifferentiated state and after type II cell differentiation induced by DCI treatment
Studies of human fetal lung in explant culture and in isolated epithelial cells have demonstrated that both glucocorticoids and cyclic AMP promote differentiated alveolar type II cell phenotype as assessed by ultrastructural morphology and surfactant production. This project profiles changes in gen...
ORGANISM(S): Homo sapiens 
2007-11-22 | E-GEOD-3306 | biostudies-arrayexpress
TranscriptomicsGlucose-depletion time-course experiment in Saccharomyces cerevisiae wild-type cells.
To investigate the glucose regulatory system in Saccharomyces cerevisiae, we conducted a time-course in which glucose-depleted wildtype (WT) cells were inoculated into fresh media (SC, 2% glucose). Their subsequent transcriptional output was monitored over a period of five hours by DNA microarrays: ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-17 | E-GEOD-33098 | biostudies-arrayexpress
ProteomicsIron flux in plasmacytoid dendritic cells; potential role for transferrin receptor beyond iron metabolism
Plasmacytoid dendritic cells (pDCs) are critical antiviral sentinels known for rapid type I interferon (IFN-I) production. However, their proteomic profile and nutrient dependencies are not well understood. Here, we used absolute quantitative proteomics of ex vivo murine splenic pDCs to characterize...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD079623 | Pride
Transferrin receptor  dendritic cell  iron 
TranscriptomicsDeletion mutant analysis of established glucose signaling and metabolic pathway members in Saccharomyces cerevisiae
To understand the organisation of the glucose regulatory system, we analysed 91 deletion mutants of established glucose signalling and metabolic pathway members in Saccharomyces cerevisiae by DNA microarrays. These deletion mutants do not induce pathway-specific transcriptional responses reflecting ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-17 | E-GEOD-33097 | biostudies-arrayexpress
ProteomicsA proteomic atlas of insulin signaling reveals tissue-specific mechanisms of longevity-assurance
Lowered activity of the insulin/IGF signaling (IIS) network can ameliorate the effects of ageing in model organisms and, possibly, humans. Remodelling of the RNA transcriptome of long-lived IIS mutants has been extensively documented, but is only weakly predictive of consequent changes in protein ex...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2017-09-13 | PXD006225 | Pride
Q exactive Insulin signaling Tissue specific Shotgun Drosophila melanogaster 
TranscriptomicsMicroarray analysis of RNA of TCR transgenic CD8 T cells to assess the role of protein glycosylation in the decision between deletion vs. anergy in immune tolerance
Activation of peripheral T lymphocytes in the absence of pathogen induced inflammation or costimulatory signals results in tolerance. Two different tolerance mechanisms have been described, deletion and anergy. We recently demonstrated that an important variable which is responsible for the decisio...
ORGANISM(S): Mus musculus 
2011-09-07 | E-GEOD-31987 | biostudies-arrayexpress
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