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This experiment aims to identify the RNA-binding proteome that is pulled-down from a cellular lysate with biotinylated RNA probes.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-21 | PXD030720 | Pride
This experiment aims to identify the RNA-binding proteome that is pulled-down from a cellular lysate with biotinylated RNA probes.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-30 | PXD025492 | Pride
Fragment-sequencing unveils local tissue microenvironments at single cell resolution
Analysis of HL60 response to low-dose vincristine at gene expression level. The hypothesis tested in the present study was that population heterogeneity has functional consequences in drug response. Since the presence of discrete efflux^High and efflux^Low subpopulations may reflect transitions betw...
ORGANISM(S): Homo sapiens 
Canonical Wnt signaling output is mediated by β-catenin, which interacts with LEF/TCF transcription factors and recruits a general transcriptional activation complex to its C-terminus. Its N-terminus binds BCL9/9L proteins, which bind co-activators that in mammals contribute to fine-tuning the tran...
ORGANISM(S): Mus musculus 
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Senescent cells secrete a variety of pro inflammatory factors in the tumor microenvironment, which can support the survival, outgrowth and migration of tumor cells. Here we examine cytokines and cytokines...
ORGANISM(S): Mus musculus 
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Here we examine the cellular senescence response in epithelial individual cells, by single-cell RNA sequencing (scRNAseq) in Ptenpc-/- and Ptenpc-/-; Timp1-/- GEMMs. ScRNAseq analysis determines a cluste...
ORGANISM(S): Mus musculus 
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