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ProteomicsOlfactory bulb proteome characterization in APP/PS1 mice
Here we used double-transgenic amyloid precursor protein/presenilin 1 (APPswe/PS1dE9) mice and label-free quantitative proteomics to analyze potential early pathological effects on the olfactory bulb (OB) during AD progression.
ORGANISM(S): Mus musculus (Mouse) 
2016-08-09 | PXD003683 | Pride
Olfactory bulb Proteomics 
UnknownA High-Performance and Cost-Effective Field Programmable Gate Array-Based Motor Drive Emulator
Not available
S-EPMC10608923 | biostudies-literature
ProteomicsGlioma proteome organization under oncolytic adenoviral infection
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to enhance tumor tropism and glioma-selective replication. E1A mutant adenovirus Delta-24-RGD has shown fa...
ORGANISM(S): Homo sapiens (Human) 
2018-10-22 | PXD008022 | Pride
Proteomics Glioma Adenovirus 
Proteomicsnuclear proteomics of glioma cells infected with an oncolytic adenovirus
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to enhance tumor tropism and glioma-selective replication. E1A mutant adenovirus Delta-24-RGD has shown fa...
ORGANISM(S): Homo sapiens (Human) 
2018-10-22 | PXD008023 | Pride
Proteomics Nuclear fraction Glioma Adenovirus 
ProteomicsModulation of glioma cell proteome by Delta-24-RGD adenovirus (48hpi)
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to enhance tumor tropism and glioma-selective replication. E1A mutant adenovirus Delta-24-RGD has shown fa...
ORGANISM(S): Homo sapiens (Human) 
2018-12-11 | PXD010256 | Pride
Glioma Proteomics Adenovirus 
ProteomicsOlfactory proteomics in Parkinson disease
Olfactory dysfunction is one of the earliest features in Lewy-type alpha-synucleinopathies (LTS) such as Parkinson´s disease (PD). However, the underlying molecular mechanisms associated to smell impairment is poorly understood. To reveal the missing links in the biochemical understanding of olfacto...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD008036 | Pride
Proteomics Olfactory bulb Parkinson 
ProteomicsOlfactory bulb proteomics in human Alzheimer's disease
Olfactory dysfunction is among the earliest features of Alzheimer´s disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here, OB- proteome analysis was performed across different AD stages using a label-free...
ORGANISM(S): Homo sapiens (Human) 
2018-01-16 | PXD005319 | Pride
Proteomics Olfactory bulb 
Proteomicsolfactory proteomics in aged Tg2576 mice
Olfaction is often deregulated in Alzheimer´s disease (AD) patients, being also impaired in transgenic Tg2576 AD mouse model, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little is known about the molecular mechanisms that accompany the neurodegenerat...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-02 | PXD007795 | Pride
Alzheimer Olfactory bulb Proteomics Neurodegeneration 
ProteomicsTime-dependent olfactory proteomics in Tg2576 mice
Olfaction is often deregulated in Alzheimer´s disease (AD) patients, being also impaired in transgenic Tg2576 AD mouse model, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little is known about the molecular mechanisms that accompany the neurodegenerat...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-28 | PXD007813 | Pride
Olfactory bulb Proteomics Alzheimer 
UnknownSynthesis, Characterization, and Intrinsic Dissolution Studies of Drug-Drug Eutectic Solid Forms of Metformin Hydrochloride and Thiazide Diuretics.
Not available
S-EPMC8620433 | biostudies-literature
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