Sort   by:  
 Page size 
MetabolomicsHigh-performance nano-flow liquid chromatography column combined with high- and low-collision energy data-independent acquisition enables targeted and discovery identification of modified ribonucleotides by mass spectrometry (Mixed-mode column chromatography)

Over 170 post-transcriptional RNA modifications have been described and are common in all kingdoms of life. These modifications range from methylation to complex chemical structures, with methylation being the most abundant. RNA modifications play a key role in RNA folding and function and their ...

2023-10-26 | MTBLS2497 | MetaboLights
MetabolomicsHigh-performance nano-flow liquid chromatography column combined with high- and low-collision energy data-independent acquisition enables targeted and discovery identification of modified ribonucleotides by mass spectrometry (Data-independent acquisition)

Over 170 post-transcriptional RNA modifications have been described and are common in all kingdoms of life. These modifications range from methylation to complex chemical structures, with methylation being the most abundant. RNA modifications play a key role in RNA folding and function and their ...

2023-10-26 | MTBLS2959 | MetaboLights
ProteomicsA Quantitative Chemical Proteomics Approach Using a Novel Two-Probe System Enables System-Wide Analysis of Protein Prenylation
Proteins prenylation, the post-translational attachment of a farnesyl or geranylgeranyl isoprenoid to one or more C-terminal cysteine residues, is an important modulator of localization and function of proteins such as the Ras isoforms, and a widely studied therapeutic target in number of cancer and...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-03-29 | PXD009155 | Pride
Human Prenylation Chemical proteomics 
ProteomicsBeauveria bassiana manipulates host plant physiology to promote growth and defense
During plant life, roots support beneficial associations with soil inhabiting microbes, mainly fungi and bacteria. Increasing evidence suggests that plant-associated microorganisms can promote plant growth and expand immune functions of the plant host. The beneficial entomopathogenic fungus Beauveri...
ORGANISM(S): Solanum lycopersicum 
2023-05-09 | PXD029422 | Pride
Proteomics Beauveria bassiana Tomato leaves Solanum lycopersicum l. Mass-spectrometry 
ProteomicsInhibition of protein N-myristoylation blocks Plasmodium falciparum intracellular development and egress, but myristoylation of GAP45 is required only for erythrocyte invasion.
In this project, the aim was to investigate the effect of NMT inhibition during schizogony, synchronized parasite populations.
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-10-07 | PXD022704 | Pride
Lc-ms/ms N-myristoylation Plasmodium faciparum 
ProteomicsQuantitative chemical proteomic analysis of YnMyr-tagged proteins in HeLa cells infected with RV16
Rhinovirus causes the common cold and drives exacerbation in asthma and COPD, leading to substantial morbidity and healthcare cost. The single positive strand RNA genome of this non-enveloped virus is translated into a single polyprotein that is processed by virus 3C protease to form three structura...
ORGANISM(S): Homo sapiens (Human) 
2018-05-09 | PXD005798 | Pride
Hela Rv16 Proteomics Myristoylation Nmt inhibition 
ProteomicsN-Myristoyltransferase inhibition in HeLa
N-Myristoyltransferase (NMT) covalently attaches a C14-fatty acid to the N-terminal glycine of proteins and has been proposed as a therapeutic target in cancer. We used quantitative proteomics to map protein expression changes for more than 2700 proteins in response to treatment with an NMT inhibito...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080783 | MassIVE
UnknownPost-exposure vaccine effectiveness and contact management in the mpox outbreak, Madrid, Spain, May to August 2022.
Not available
S-EPMC10318941 | biostudies-literature
UnknownDaily tenofovir disoproxil fumarate/emtricitabine and hydroxychloroquine for pre-exposure prophylaxis of COVID-19: a double-blind placebo-controlled randomized trial in healthcare workers.
Not available
S-EPMC9352647 | biostudies-literature
UnknownEfficacy and safety of a booster dose of influenza vaccination in solid organ transplant recipients, TRANSGRIPE 1-2: study protocol for a multicenter, randomized, controlled clinical trial.
Not available
S-EPMC4159520 | biostudies-literature
Sort   by:  
 Page size