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ProteomicsSecretome analysis of basidiomycetous yeast Tausonia pullulans growing on glucose and starch
We performed the genomic sequencing, assembly and annotation of T. pullulans strain CRUB 1754 (Perito Moreno glacier, Argentina), a gene survey of Carbohydrate-active enzymes (CAZymes); and analyzed its secretome by Liquid-Chromatography coupled to tandem Mass Spectrometry (LC-MS/MS) after growth in...
ORGANISM(S): Tausonia pullulans 
2022-12-02 | PXD031068 | Pride
Starch Tausonia Glucose Secretome 
ProteomicsEnsured auxin sensing by degron flexibility
Using a structural proteomics approach via chemical cross-linking combined with mass spectrometry (XL-MS), we have resolved SCFTIR auxin·AUX/IAA complex overall topology, and established the power of IDRs modulating auxin receptor assemblies.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-11 | PXD015285 | Pride
Auxin Cross-linking Iaa12 Auxin receptor Xl-ms Idrs Indole-3-acetic acid Aux/iaas Iaa7 Scf-type e3 ubiquitin ligase Tir1 
TranscriptomicsElevated expression of the H3K36me2 demethylase Kdm8/Jmjd5, a direct Miz1 target gene causes prolonged postnatal Schwann cell proliferation in the murine Miz1∆POZ neuropathy
The deletion of the POZ domain of the transcription factor Miz1 leads to a late onset neuropathy with subsequent spontaneous regeneration in mice. In this study, we aim to identify genes that are involved in the development of this neuropathy. We traced first gene regulatory changes in sciatic nerve...
ORGANISM(S): Mus musculus 
2018-03-14 | E-MTAB-5600 | biostudies-arrayexpress
GenomicsA Genomic History of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterised. We generated high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25...
EGAS00001001766 | EGA
TranscriptomicsFollicular lymphoma in situ and partial involvement by follicular lymphoma are clona lesions that carry the t(14;18) and lack genetic secondary alterations
Follicular lymphoma (FL) is characterized by the t(14;18)(q32;q21), frequent numerical chromosomal alterations, and recurrent somatic mutations. However, no genetic studies are available for FL in situ (FLIS), a putative precursor lesion of FL. In this study, we analyzed cases of FLIS without manife...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-48548 | biostudies-arrayexpress
UnknownTargeting the extra domain A of fibronectin for cancer therapy with CAR-T cells.
Not available
S-EPMC9351345 | biostudies-literature
UnknownCoupled C, H, N, S and Fe biogeochemical cycles operating in the continental deep subsurface of the Iberian Pyrite Belt.
Not available
S-EPMC10107794 | biostudies-literature
UnknownAnnexin A8 deficiency delays atherosclerosis progression.
Not available
S-EPMC11748212 | biostudies-literature
UnknownId1 and PD-1 Combined Blockade Impairs Tumor Growth and Survival of KRAS-mutant Lung Cancer by Stimulating PD-L1 Expression and Tumor Infiltrating CD8+ T Cells.
Not available
S-EPMC7693788 | biostudies-literature
TranscriptomicsMicroRNA expression profile in macrophages from rheumatoid arthritis and osteoarthritis patients
In osteoarthritis (OA) and rheumatoid arthritis (RA), many pathological alterations result from aberrant macrophage hyperactivation in the inflamed synovial membrane, and inhibition of macrophage effector functions is a therapeutic strategy in both diseases. Little is known, about the specific gene...
ORGANISM(S): Homo sapiens 
2016-02-05 | E-GEOD-63745 | biostudies-arrayexpress
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