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Neuroblastoma cell lines genetically modified to overexpress Anaplastic lymphoma kinase (ALK) point mutations or the ALK wild-type isoform were injected subcutaneously or orthotopically into NOD-SCID-gamma or athymic Swiss nude mice, respectively. After development of the tumor, RNA was extracted fr...
ORGANISM(S): Mus musculus 
In this study, merging in silico transcriptomic data and in situ TMA studies, we first highlighted the clinical significance and the value as prognostic factors of the embryonic TFs TWIST1 and TWIST2, thus linking their level of expression with the outcome of NB patients. Secondly, using NB cells k...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD024200 | Pride
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