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MetabolomicsBridging Targeted (Zeno MRM-HR) and Untargeted (SWATH) LC–HRMS in a Single Run for Sensitive Exposomics

Traditionally, chemical exposure has been assessed by low-resolution mass spectrometry via targeted approaches due to the typically extremely low concentration of such compounds in biological samples. Nevertheless, untargeted approaches are now becoming a promising tool for a broader investigatio...

2025-08-28 | MTBLS10565 | MetaboLights
GenomicsBifidobacterium jacchi strain:MRM 9.3
Bifidobacterium jacchi strain:MRM 9.3 Genome sequencing and assembly
PRJNA506375 | ENA
ProteomicsiTRAQ-MRM approach identify plasma biomarkers of atherosclerosis and myocardial injury
Current methods of stratifying patient risk of myocardial injury and stable angina rely on complex combinations of risk factors that exhibit only limited prognostic power, hence there remains a need to identify biomarkers that can be sampled non-invasively and more accurately predict patient outcome...
ORGANISM(S): Homo sapiens (Human) 
2018-11-06 | PXD006333 | Pride
Myocardial injury Mrm Cardiovascular disease Angina Atherosclerosis Itraq Plasma biomarker 
ProteomicsHuman tissue microsomed by MRM, MRMHR and SWATH
The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane-associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney and intestine by means of SWATH-MS with stable i...
ORGANISM(S): Homo Sapiens (human) 
2018-01-01 | PXD008265 | JPOST Repository
ProteomicsMRM (Multiple Reaction Monitoring) quantitation of the blood plasma and serum samples from healthy donors
Using 30 synthetic bacterial peptides as external standards, we quantified the abundance of identified peptides in the serum and plasma by multiple reaction monitoring (MRM). Of these 30 peptides, 15 were quantified reliably.
ORGANISM(S): Homo sapiens (Human) 
2024-06-14 | PXD027793 | Pride
Peptidomics Multiple reaction monitoring Mass spectrometry Mrm Blood plasma and serum Healthy donors 
GenomicsBifidobacterium catulorum strain:MRM 8.19
Bifidobacterium catulorum strain:MRM 8.19 Genome sequencing and assembly
PRJNA464312 | ENA
ProteomicsQuantification of cytokines secreted by primary human cells using MRM: evaluation of analytical parameters â?? shotgun secretome data of untreated HUVECs
The determination of secreted proteins may provide highly valuable information about cell functions. While the typical methods for the determination of biologically relevant but low-abundant molecular species still relies on the use of specific antibodies, mass spectrometry-based methods are now gai...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079983 | MassIVE
ProteomicsQuantification of cytokines secreted by primary human cells using MRM: evaluation of analytical parameters â?? shotgun secretome data of inflammatory stimulated HUVECs
The determination of secreted proteins may provide highly valuable information about cell functions. While the typical methods for the determination of biologically relevant but low-abundant molecular species still relies on the use of specific antibodies, mass spectrometry-based methods are now gai...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079982 | MassIVE
ProteomicsImpacts of HLA-B57 micropolymorphism (MRM)
Comparison of peptide ligands of major histocompatibility class (MHC) I isolated by immunoaffinity purification from the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the MHC class I alleles HLA-B*57:01, HLA-B*57:03 and HLA-B*58:01.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD009850 | Pride
Mhc Mrm Immunopeptidome Hla-b57 
ProteomicsQuantification of oxidative stress-related proteins using MRM approach in atherosclerosis-related and non-related to chronic kidney disease
The aim of MRM analysis of selected oxidative stress-related proteins, including MPO, CERu, sTNF, SOD3, HMOX1, PON1, GPX3, NOS2, CAT and IFNG was to investigate changes in plasma samples from patients at different stages of atherosclerosis-related to chronic kidney disease, classical atherosclerosis...
ORGANISM(S): Homo sapiens (Human) 
2024-01-23 | PXD041820 | Pride
Ckd Mrm Plasma Atherosclerosis Oxidative stress 
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