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TranscriptomicsAnti-Inflammatory Effects of Budesonide in Human Fetal Lung
Rationale. Lung inflammation in premature infants contributes to development of bronchopulmonary dysplasia (BPD), a chronic lung disease with long-term sequelae. Pilot studies administering budesonide suspended in surfactant have found reduced BPD without apparent adverse effects as occur with syste...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-83888 | biostudies-arrayexpress
ProteomicsFASIL-MS: An Integrated Proteomic and Bioinformatic Workflow to Universally Quantitate In vivo-acetylated Positional Isomers
Dynamic changes in histone post-translational modifications (PTMs) regulate gene transcription leading to fine-tuning of biological processes such as DNA replication and cell cycle progression. Moreover, specific histone modifications constitute docking sites for recruitment of DNA damage repair pr...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2016-06-16 | PXD003611 | Pride
Ms2-based quantitation Lysine deacetylase inhibitor Histone acetylation Mass spectrometry N-acetoxy-d3-sucinnimide Fasp Protein derivatisation 
ProteomicsSpatial omics based machine learning (SOML) algorithms for the early detection of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is the seventh most common cancer in the world and accounts for over 800,000 deaths annually, making it the second most lethal cancer. Poor chemotherapeutic agents against HCC have necessitated the importance of early detection and surgical intervention in patient mana...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047546 | Pride
Glycan Spatial-omics Hcc Imaging Maldi_tof 
ProteomicsIntegrative Personal Omics Profiles During Periods of Weight Gain and Loss
A longitudinal study of PBMCs from patients during periods of weight gain and loss in humans was performed.
ORGANISM(S): Homo sapiens (Human) 
2018-01-11 | PXD007859 | Pride
Pbmc Tmt Lc-ms/ms 
ProteomicsCarrier protein-enabled host cell proteome analysis (CP-HCP) with integrated isobaric tag interference filtering
We used TMT labelling to set up different experiment channels containing mixtures of the host cell carrier proteome (E coli) and mock biotherapeutic (BSA), to compare with interference detection channel to model and filter interference, a phenomenon where host cell proteins (HCPs) co-elute with high...
ORGANISM(S): Escherichia coli 
2026-01-12 | PXD049970 | Pride
Boost Host cell proteins Multi-plexed proteomics Tmt Carrier proteome Lc-ms Co-isolation Interference Co-fragmentation Dda 
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