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MetabolomicsPost-herbivory Tea Plant Leaves Restructure Endophytic Microbiota to Resist Disease and Boost Saccharide Metabolism to Promote Growth

The induced capacity of plant growth-defense trade-offs under biotic stress is increasingly recognized. While many studies mainly focus on plants’ defense activation stage during insect attacks, limited attention has been given to post-stress recovery. Herein, leaves from normal and post-herbivor...

2025-07-02 | MTBLS12664 | MetaboLights
ProteomicsProteome-wide detection of cysteine nitrosylation targets and motifs using bio-orthogonal cleavable linker based enrichment and switch technique (Cys-BOOST)
Cysteine (Cys) reversible post-translational modifications (PTMs) are emerging as important players in cellular signaling and redox homeostasis. Here we present Cys-BOOST a novel strategy for LC-MS/MS based quantitative analysis of reversibly modified Cys using switch technique, enrichment via bio-o...
ORGANISM(S): Homo sapiens (Human) 
2019-05-21 | PXD011131 | Pride
Cysteine Nitrosylation Ptm 
GenomicsCell type characterization of Boost and Boost+ mDA neuron protocol in vitro and in grafted in unilateral 6-hydroxydopamine (OHDA)-induced Parkinsonian rats
Cell type characterization of Boost and Boost+ mDA neuron protocol in vitro and in grafted in unilateral 6-hydroxydopamine (OHDA)-induced Parkinsonian rats
PRJEB83838 | ENA
TranscriptomicsCell type characterization of Boost and Boost+ mDA neuron protocol in vitro and in grafted in unilateral 6-hydroxydopamine (OHDA)-induced Parkinsonian rats
This work presents an optimized mDA neuron differentiation strategy that builds on the clinical grade (“Boost”) protocol but includes the addition of FGF18 and IWP2 treatment (“Boost+”) at the mDA neurogenesis stage. Both protocols were characterized by single-nucleus RNA-seq and compared in terms o...
ORGANISM(S): Homo sapiens 
2026-03-10 | E-MTAB-14729 | biostudies-arrayexpress
TranscriptomicsNK cell immune responses differ after prime and boost vaccination
A better understanding of innate responses induced by vaccination is critical for designing optimal vaccines. Here, we studied the diversity and dynamics of the NK cell compartment after prime-boost immunization with the modified vaccinia virus Ankara using cynomolgus macaques as a model. Mass cytom...
ORGANISM(S): Macaca fascicularis 
2019-02-19 | E-MTAB-7697 | biostudies-arrayexpress
ProteomicsMice primary T cell phosphotyrosine proteomics enabled by BOOST
Signal propagation mediating numerous cellular processed in T cells is orchestrated by tyrosine phosphorylation with a high degree of regulation1, 2. Because aberrant tyrosine phosphorylation can result in many diseases3, a method to systematically quantify this dynamic process can be helpful in und...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-04 | PXD025853 | Pride
T cell Boost Phosphotyrosine proteomics Tmt Mice 
TranscriptomicsmRNA expression profiles of antigen-specific CD8+ T cells induced by DNA prime-DNA boost and DNA prime-VACV boost immunization regimen
Similar with others, our data proved that antigen-specific CD8+ T cells from mice primed with DNA and boosted by VACV were much more sensitive to antigen stimulation than those from DNA-boost. Since the mechanisms of in vivo tuning of antigen sensitivity (also termed functional avidity) is still not...
ORGANISM(S): Mus musculus 
2013-10-30 | E-GEOD-51849 | biostudies-arrayexpress
GenomicsSplenic memory CD8 T cell signature of enhanced responsiveness to vaccine boost
Splenic memory CD8 T cell signature of enhanced responsiveness to vaccine boost
PRJNA854971 | ENA
TranscriptomicsmRNA expression profiles of antigen-specific CD8+ T cells induced by DNA prime-DNA boost and DNA prime-VACV boost immunization regimen
Similar with others, our data proved that antigen-specific CD8+ T cells from mice primed with DNA and boosted by VACV were much more sensitive to antigen stimulation than those from DNA-boost. Since the mechanisms of in vivo tuning of antigen sensitivity (also termed functional avidity) is still not...
ORGANISM(S): Mus musculus 
2013-10-30 | GSE51849 | GEO
TranscriptomicsThe Path to Triacylglyceride Obesity in the sta6 Strain of Chlamydomonas reinhardtii
When the sta6 (starch-null) strain of the green microalga Chlamydomonas reinhardtii is nitrogen-starved in acetate and then "boosted" after two days with additional acetate, the cells become "obese" after eight days, with triacylglyceride-filled lipid bodies filling their cytopla...
ORGANISM(S): Chlamydomonas reinhardtii 
2014-03-09 | E-GEOD-55253 | biostudies-arrayexpress
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