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ProteomicsDeciphering the dynamic proteome of multiciliated cells
Multiciliated cells (MCCs) are essential for generating directional fluid flow across specialized epithelia in various vertebrate organs. MCC differentiation involves a unique, tightly regulated program characterized by massive centriole amplification, independently of DNA replication. Although much...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2026-02-06 | PXD064476 | Pride
Lc-msms Multiciliated cells proteome (mcc) Deuterosome Centriole Xenopus 
GenomicsEdf1 control multiciliated ependymel cell associated genes expression
Edf1 control multiciliated ependymel cell associated genes expression
PRJNA1026381 | ENA
GenomicsIL-4 drastically decreases deuterosomal and multiciliated cells via alteration in progenitor cell differentiation
IL-4 drastically decreases deuterosomal and multiciliated cells via alteration in progenitor cell differentiation
PRJNA1028120 | ENA
TranscriptomicsRNAseq profiling of multiciliated cells
To determine what genes are upregulated in multiciliated cells, we manipulated Xenopus laevis ectoderm to either make more or fewer of this cell type with multiple approaches across multiple timepoints. By finding differentially expressed genes in common across all comparisons in which multiciliated...
ORGANISM(S): Xenopus laevis 
2015-12-25 | GSE76342 | GEO
TranscriptomicsExpression data of kidney multiciliated cells from zebrafish embryos
Multiciliated cells (MCCs) possess multiple motile cilia on the cell surface and are widely distributed throughout the vertebrate body to perform important physiological functions by regulating fluid movement in the intercellular space. However, neither their function during organ development nor th...
ORGANISM(S): Danio rerio 
2013-05-11 | E-GEOD-46844 | biostudies-arrayexpress
TranscriptomicsMiR-34b regulates multiciliogenesis during organ formation in zebrafish
Multiciliated cells possess multiple motile cilia on the cell surface and are widely distributed throughout the vertebrate body to perform important physiological functions by regulating fluid movement in the intercellular space. However the molecular mechanisms underlying multiciliogenesis are not ...
ORGANISM(S): Danio rerio 
2013-06-14 | E-MEXP-3893 | biostudies-arrayexpress
UnknownDeup1 Expression Interferes with Multiciliated Differentiation.
Not available
S-EPMC10701303 | biostudies-literature
TranscriptomicsExpression of Piwi protein MIWI2 defines a distinct population of multiciliated cells
We find that MIWI2 protein is expressed in a discrete population of multiciliated airway epithelial cells of the lung. The isolation and the next generation sequencing of the MIWI2-positive multiciliated cells revealed that they are phenotypically distinct from neighboring MIWI2-negative multiciliat...
ORGANISM(S): Mus musculus 
2017-09-19 | GSE101806 | GEO
UnknownRegulation of cilia abundance in multiciliated cells.
Not available
S-EPMC6504233 | biostudies-literature
UnknownSpontaneous Calcium Bursts Organize the Apical Actin Cytoskeleton of Multiciliated Cells.
Not available
S-EPMC11942550 | biostudies-literature
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