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TranscriptomicsHistone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast.
In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its SRI domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser2 and Ser5 (CTD-S2,5-P). H3K36me2 recruits the Rpd3S histone deacetylase complex to repress crypt...
ORGANISM(S): Schizosaccharomyces pombe 
2016-02-04 | E-GEOD-66821 | biostudies-arrayexpress
ProteomicsPeriodontal pathogen induces entero-hepatic metabolic derangements in type 2 diabetic mouse model
This is the first report of the metabolic and metaproteomic integrated changes in the gut and liver by the swallowed periodontopathogen. Periodontal disease pathogen Porphyromonas gingivalis are observed in faeces as peptides level in proteomic analysis and make changes in bowel microbial compositio...
ORGANISM(S): Cellular Organisms 
2021-09-21 | PXD021851 | JPOST Repository
TranscriptomicsGenomic profiles of oxidative stress-induced rat renal cell carcinomas
Intraperitoneal administration of ferric nitrilotriacetate (Fe-NTA) initiates Fenton reaction in the renal proximal tubules of rodents that ultimately leads to a high incidence of renal cell carcinoma (RCC) after repeated treatment. We performed high-resolution microarray comparative genomic hybridi...
ORGANISM(S): Rattus norvegicus 
2012-08-30 | E-GEOD-36101 | biostudies-arrayexpress
UnknownDeciphering OPDA Signaling Components in the Momilactone-Producing Moss Calohypnum plumiforme.
Not available
S-EPMC8201998 | biostudies-literature
ProteomicsChronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.
There is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-29 | PXD035613 | JPOST Repository
UnknownCommunity-Level Compact City Design, Health Care Provision, and Outcomes of Patients With Stroke.
Not available
S-EPMC12449981 | biostudies-literature
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