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MetabolomicsMurine gut bile acid analysis
Not available
ORGANISM(S): Mus musculus 
ST000212 | MetabolomicsWorkbench
TranscriptomicsGene expression changes in murine ileum during inflammation: Controls vs. intestinal schistosomiasis and TNBS-ileitis.
Background: Although a number of intestinal inflammatory conditions pertain to the ileum, whole-genome gene expression analyses on ileal inflammation in animal models are lacking to date. Therefore, we aimed to identify and characterize alterations in gene expression in the acutely inflamed ileum of...
ORGANISM(S): Mus musculus 
2012-10-05 | E-GEOD-31265 | biostudies-arrayexpress
TranscriptomicsExpression data from ileum of mice suffered from subchronic and mild social defeat stress
This study aimed to investigate the effects of depression on transcriptome in ileum using a subchronic and mild social defeat stress (sCSDS) model. In addition to exhibiting social deficit and hyperphagia-like behavior, the sCSDS mice keep much more water in their body than control mice. In order to...
ORGANISM(S): Mus musculus 
2016-08-03 | E-GEOD-64004 | biostudies-arrayexpress
TranscriptomicsExpression data from ileum of inducible intestine-specific GATA6 knockout mice
GATA6 is a transcription factor involved in the differentiation of intestinal epithelial cells into differentiated absorptive epithelial cells. GATA6 is expressed in all segments of the small intestine. We examined the impact of deleting GATA6 from intestinal epithelial cells of the adult ileum 6-8...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-22416 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of intestinal epithelial cells from paediatric biopsies including Inflammatory Bowel disease and healthy controls
We purified the intestinal epithelial cells from biopsies taken from the ileum and colon of a paediatric cohort of IBD patients and healthy controls
ORGANISM(S): Homo sapiens 
2017-10-20 | E-MTAB-5463 | biostudies-arrayexpress
TranscriptomicsEffect of interferon-gamma (IFNg) deficiency in murine small intestine (ileum)
Gene expression profiling of C57Bl/6 wild type and IFNg-deficient whole ileum at 8 weeks of age 5 wild type control, 5 IFNg knockout
ORGANISM(S): Mus musculus 
2016-07-16 | E-GEOD-69635 | biostudies-arrayexpress
ProteomicsA new life-saving role for Glucocorticoid Receptor dimers: repressing STAT1-induced IFN response in the gut
The use of glucocorticoids (GCs), which bind and activate the glucocorticoid receptor (GR), in systemic inflammatory response syndromes (SIRS) is disputed. Mice with a poor transcriptional response of dimer-dependent GR target genes were studied in a model of TNF-induced SIRS. These GR dim/dim mice ...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-01 | PXD008608 | Pride
Isg Inflammatory response Murine ileum Sirs Shotgun proteomics 
TranscriptomicsTranscription profiling of Hsd:ICR(CD-1) mouse intestines to study regional variations in ABC transporter expression along the mouse intestinal tract.
8 week-old male Hsd:ICR(CD-1) mice were fed ad libitum a standard chow (Harlan Teklad diet 2018S) and housed in groups of five. Animals were then divided into 3 pools (n=10) and sacrificed. The small intestine was extracted and divided into three sections, where the first 2-3 cm after the stomach co...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-849 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of subepithelial myofibroblasts from mouse ileum or colon, implanted together with human cancer cells in mouse xenografts
We isolated myofibroblasts from C57BL6/J mouse ileum or colon and analyzed gene expression profiles from the cultured cells. We also isolated human colon cancer cells from xenografts interacting with mouse intestinal subepithelial myofibroblasts (ISEMFs) and analyzed gene expression in sorted human ...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-27564 | biostudies-arrayexpress
TranscriptomicsRegulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut
Alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the conserved microbial functions that influence host energy metabolism and adiposity have not been determined. Here we show that bacterial bile salt hydrolase (BSH) controls a microbe-host dialogu...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-46952 | biostudies-arrayexpress
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