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MetabolomicsMultiple acyl-coA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection

The human pathogen Mycobacterium tuberculosis (Mtb) devotes a significant fraction of its genome to fatty acid metabolism. Although Mtb depends on host fatty acids as a carbon source, fatty acid b-oxidation is mediated by genetically redundant enzymes, which has hampered the development of antitu...

2021-09-29 | MTBLS2374 | MetaboLights
OtherComprehensive temporal protein dynamics during the diauxic shift in Saccharomyces cerevisiae
Data from ProteomeXchange, PXD ID: PXD002093. File: m04675.mzml. Published as part of Mol Cell Proteomics. 2015 Jun 15 . From the Abstract: {{i}} Yeast (Saccharomyces cerevisiae) has served as a key model system in biology and as a benchmark for omics technology. Although near-complete proteomes of...
ORGANISM(S): Yeast 
GPM11210039772 | GPMDB
Resource Reanalysis 
OtherComprehensive temporal protein dynamics during the diauxic shift in Saccharomyces cerevisiae
Data from ProteomeXchange, PXD ID: PXD001338. File: Hap2_fraction_5.mzml. Published as part of Mol Cell Proteomics. 2015 Jun 15 . From the Abstract: {{i}} Yeast (Saccharomyces cerevisiae) has served as a key model system in biology and as a benchmark for omics technology. Although near-complete pro...
ORGANISM(S): Yeast 
GPM32320015932 | GPMDB
Resource Reanalysis 
UnknownAutism spectrum disorder symptom expression in individuals with 3q29 deletion syndrome.
Not available
S-EPMC9789637 | biostudies-literature
UnknownE1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx- ECOG-ACRIN Cancer Research Group.
Not available
S-EPMC5455313 | biostudies-literature
UnknownAlternative Splicing Shapes the Phenotype of a Mutation in BBS8 To Cause Nonsyndromic Retinitis Pigmentosa.
Not available
S-EPMC4405636 | biostudies-literature
UnknownSafety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.
Not available
S-EPMC4397277 | biostudies-literature
UnknownThe Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina.
Not available
S-EPMC4991804 | biostudies-literature
TranscriptomicsU2AF1 mutations alter splice site recognition in hematological malignancies
Whole-exome sequencing studies have identified common mutations affecting genes encoding components of the RNA splicing machinery in hematological malignancies. Here, we sought to determine how mutations affecting the 3' splice site recognition factor U2AF1 altered its normal role in RNA splicing. W...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58871 | biostudies-arrayexpress
ProteomicsProteomics of serotonergic autoregulation
Serotonin regulates its own production, degradation and release in the Raphe nuclei of the brain mainly by modifying the level and activity of autoreceptors on serotonin-producing neurons, such as 5-HT1A and 5-HT1B. This autoregulation is probably the reason for the delayed response of patients with...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055579 | Pride
Serotonin Serotonin transporter Brain Tryptophan hydroxylase Autoregulation Mouse 
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