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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
ProteomicsMulti-omics approaches reveal TNF-mediated inhibition of tissue reparative macrophages is via a gene-selective transcriptional mechanism
Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis and Crohn’s Disease. Previously, we and others found that TNF blocks the emergence and function of alternatively-activated or M2 macrophages involved in wound healing and tissue-reparative func...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-07 | PXD028667 | Pride
Tnf M2 Heterogeneity Jnk Jun Macrophage Glycolysis 
TranscriptomicsXenobiotics and loss of cell adhesion drives distinct transcriptional outcomes by Aryl hydrocarbon Receptor (AhR) signaling.
The Aryl hydrocarbon Receptor (AhR) is a signal regulated transcription factor, which is canonically activated by the direct binding of xenobiotics. In addition, switching cells from adherent to suspension culture also activates the AhR, representing a non-xenobiotic, physiological activation of AhR...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-37144 | biostudies-arrayexpress
Unknown"Trying to develop a better workforce": Stakeholders' perspectives of a practice-integrated Australian hospital pharmacist foundation residency program.
Not available
S-EPMC9212144 | biostudies-literature
TranscriptomicsNovel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection
Pathogens target phytohormone signalling pathways to promote disease. Plants deploy salicylic acid (SA) mediated defences against biotrophs. Pathogens antagonise SA immunity by activating jasmonate signalling, e.g. Pseudomonas syringae pv. tomato DC3000 produces coronatine (COR), a jasmonate (JA) mi...
ORGANISM(S): Arabidopsis thaliana 
2015-08-28 | E-GEOD-72461 | biostudies-arrayexpress
UnknownGenomic epidemiology of Streptococcus pneumoniae serotype 16F lineages.
Not available
S-EPMC10711320 | biostudies-literature
UnknownWorking together in Aboriginal health: a framework to guide health professional practice.
Not available
S-EPMC7329497 | biostudies-literature
UnknownCo-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides.
Not available
S-EPMC2268938 | biostudies-literature
UnknownCommunity Engagement and Psychometric Methods in Aboriginal and Torres Strait Islander Patient-Reported Outcome Measures and Surveys-A Scoping Review and Critical Analysis.
Not available
S-EPMC9407920 | biostudies-literature
UnknownNucleic Acid Preservation Card Surveillance Is Effective for Monitoring Arbovirus Transmission on Crocodile Farms and Provides a One Health Benefit to Northern Australia.
Not available
S-EPMC9227548 | biostudies-literature
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