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Genomicscoculture SAEC and HMVEC exposed to MWCNT
coculture SAEC and HMVEC exposed to MWCNT
PRJNA542679 | ENA
TranscriptomicsEffect of MWCNT on Lung Fibroblast gene expression
Multi-walled carbon nanotubes (MWCNT) cause lung fibrosis in rodents and exacerbate airway fibrosis in the mouse ovalbumin model of allergic asthma. Interleukin 13 (IL-13) is a key cytokine secreted by T helper type 2 (Th2) cells. IL-13 is up-regulated in human asthma and animal models that activat...
ORGANISM(S): Homo sapiens 
2013-05-29 | E-GEOD-43515 | biostudies-arrayexpress
GenomicsmiRNA profiling of lung tissues exposed to MWCNT
miRNA profiling of lung tissues exposed to MWCNT
PRJNA541431 | ENA
TranscriptomicsmRNA microarray analysis on young adult Caenorhabditis elegans exposed to MWCNT
In order to evaluate the identification of genes and pathways, the global gene expression profiles were assessed in response to multiwall carbon nanotube (MWCNT) on the soil nematode, Caenorhabditis elegans. We performed whole genome DNA microarray experiments with subsequent quantitative analysis c...
ORGANISM(S): Caenorhabditis elegans 
2011-12-31 | E-GEOD-24847 | biostudies-arrayexpress
ProteomicsToxicoproteomic and lipidomic analysis of human lung cells chronically exposed to MWCNT
Multi-walled carbon nanotubes (MWCNT) present a wide variety of exciting application opportunities. As MWCNT are produced in large quantities, occupational exposure and human health is of particular concern. However, there is no consensus regarding their potential harmful effects. In particular, chr...
ORGANISM(S): Homo sapiens (Human) 
2020-05-06 | PXD005970 | Pride
Carbon nanotubes Lc-msms Genotoxicity Toxicoproteomics Lipidomics Label free quantification Long-term exposure Apoptosis Human Mwcnt 
GenomicsmiRNA profiling of blood samples from MWCNT exposed mice
miRNA profiling of blood samples from MWCNT exposed mice
PRJNA533976 | ENA
TranscriptomicsEffect of MWCNT on Lung Fibroblast gene expression
Multi-walled carbon nanotubes (MWCNT) cause lung fibrosis in rodents and exacerbate airway fibrosis in the mouse ovalbumin model of allergic asthma. Interleukin 13 (IL-13) is a key cytokine secreted by T helper type 2 (Th2) cells. IL-13 is up-regulated in human asthma and animal models that activate...
ORGANISM(S): Homo sapiens 
2013-05-29 | GSE43515 | GEO
GenomicsmiRNA profiling of blood samples from MWCNT exposed mice
Pulmonary exposure to multiwalled carbon nanotubes (MWCNT) induces an inflammatory and rapid fibrotic response, although the long-term signaling mechanisms are unknown. The aim of this study was to examine the effects of 1, 10, 40, or 80 μg MWCNT administered by pharyngeal aspiration on bronchoalveo...
ORGANISM(S): Homo sapiens Mus musculus Macaca mulatta Rattus norvegicus 
2019-07-26 | GSE130109 | GEO
Genomicscoculture SAEC and HMVEC exposed to MWCNT
This study compared global multi-walled carbon nanotube (MWCNT)-induced miRNA expression from human lung epithelial and microvascular endothelial cells in monoculture and coculture with miRNA expression from mouse lungs exposed to MWCNT. The concordant miRNA in human cell lines, mouse lung tissues a...
ORGANISM(S): Mus musculus Homo sapiens Rattus norvegicus 
2022-04-18 | GSE131121 | GEO
GenomicsIntrinsic properties of MWCNT affect immunotoxicity in THP-1 in vitro model
Intrinsic properties of MWCNT affect immunotoxicity in THP-1 in vitro model
PRJNA910581 | ENA
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