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ProteomicsProteom-wide analysis of lysine N-homocysteinylation and Hcy-induced proteom changes in Saccharomyces cerevisiae
Hyperhomocysteinemia (HHcy) inhibits growth and is cytotoxic to bacterial, yeast, and mammalian cells. The aim of this study was to determine the changes in proteome of the yeast induced by HHcy and map N-homocysteinylated sites. We identified 38 up- and 32-down-regulated proteins as well as 244 N-h...
ORGANISM(S): Bos taurus (Bovine) Mus musculus (Mouse) Saccharomyces cerevisiae (Baker's yeast) Equus caballus (Horse) 
2021-04-08 | PXD020821 | Pride
N-homocysteinylation Homocysteine Homocysteine thiolactone Yeast proteome 
ProteomicsProteom-wide analysis of lysine N-homocysteinylation and Hcy-induced proteom changes in Saccharomyces cerevisiae - SILAC data
Hyperhomocysteinemia (HHcy) inhibits growth and is cytotoxic to bacterial, yeast, and mammalian cells. The aim of this study was to determine the changes in proteome of the yeast induced by HHcy and map N-homocysteinylated sites. We identified 38 up- and 32-down-regulated proteins as well as 244 N-h...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-16 | PXD019951 | Pride
Proteomics Lc-ms Silac N-homocysteinylation Yeast 
UnknownChemical proteomic profiling of protein N-homocysteinylation with a thioester probe.
Not available
S-EPMC5914431 | biostudies-literature
UnknownN-homocysteinylation of α-synuclein promotes its aggregation and neurotoxicity.
Not available
S-EPMC10014048 | biostudies-literature
UnknownMechanistic investigation of N-homocysteinylation-mediated protein-gold nanoconjugate assembly.
Not available
S-EPMC2833329 | biostudies-literature
UnknownComparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method.
Not available
S-EPMC5292613 | biostudies-literature
ProteomicsChemical proteomic profiling of protein N-homocysteinylation with a thioester probe
We performed quantitative chemical proteomics to identify more than 800 N-homocysteinylated proteins as well as 304 N-homocysteinylated sites directly from HTL-treated HeLa cells.
ORGANISM(S): Homo Sapiens 
2024-10-09 | PXD056640 |
UnknownThe application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects.
Not available
S-EPMC4375028 | biostudies-literature
UnknownParaoxonase 1 Phenotype and Protein N-Homocysteinylation in Patients with Rheumatoid Arthritis: Implications for Cardiovascular Disease.
Not available
S-EPMC7555791 | biostudies-literature
UnknownN-Homocysteinylation of HMGB1/2 Promotes Corpus Cavernosum Endothelial Senescence in Erectile Dysfunction.
Not available
S-EPMC12631104 | biostudies-literature
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