The project involves the purification of Nt-arginylated proteins and their interacting partners in Human cell line HMEC and T-47D. The purification was done with R-catcher.
Meningiomas are the most common primary brain tumors, yet the molecular pathways that distinguish grade 1 from grade 2 lesions remain insufficiently understood. Among post-translational modifications, N-terminal arginylation—catalyzed by ATE1—regulates protein stability and cellular stress responses...
N-terminal peptide enrichment for ATE1 knockdown mutant breast cell line. Immortalized human breast cell line HMEC, and breast cancer cell line T47D were used.
