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Pancreatic ductal adenocarcinoma (PDAC) is extraordinarily chemoresistant and the abundant stromal content of these tumors contributes to the ineffective treatment of this disease. While the genetic alterations of PDAC have been well characterized, the epigenetic pathways regulating PDAC remain, fo...
ORGANISM(S): Homo sapiens 
Environmental factors during perinatal development influence developmental plasticity and disease susceptibility via alterations to the epigenome. Developmental exposure to the endocrine active compound, bisphenol A (BPA), has previously been associated with altered methylation at candidate gene lo...
ORGANISM(S): Mus musculus 
Actinobacillus pleuropneumoniae is responsible for porcine pleuropneumoniae, a severe respiratory disease that causes major global financial losses to the swine industry every year. Phase variation is the random switching of gene expression, either ON-OFF switching of expression, or the expression o...
ORGANISM(S): Actinobacillus pleuropneumoniae serovar 7 str. AP76 Actinobacillus pleuropneumoniae serovar 3 str. JL03 
2023-05-10 | PXD036273 | Pride
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