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MetabolomicsLipidomic analysis of CD4+ T-cell subsets (Th1,Th2,Th17 and iTreg cells) (part I)
Not available
ORGANISM(S): Homo sapiens 
ST001676 | MetabolomicsWorkbench
ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
TranscriptomicsTumor-specific CD4+ T cells eradicate established melanoma
Adoptive transfer of CD4+ T cells (TRP-1 CD4+ T cells) specific for tyrp-1 (tyrosinase-related protein 1) eradicate established tumors (melanoma) in lymphopenic RAG-/- hosts. In vitro differentiated CD8+ T cells have been the primary focus of immunotherapy of cancer with little focus on CD4+ T cells...
ORGANISM(S): Mus musculus 
2010-01-14 | E-GEOD-19904 | biostudies-arrayexpress
ProteomicsTcell surface analysis - A combined omics approach to generate the surface atlas of human naive CD4+ T cells during early TCR activation
Naive CD4+ T cells are the common precursors of multiple effector and memory T cell subsets and possess a high plasticity in terms of differentiation potential. This stem-cell like character is important for cell therapies aiming at regeneration of specific immunity. Cell surface proteins are crucia...
ORGANISM(S): Homo sapiens (Human) 
2015-05-27 | PXD001432 | Pride
T-cells 
TranscriptomicsGene expression profiles of antigen-specific CD4+ T cells from mice carrying T cell-specific deletions of MyD88 or IL6Ra
2W:I-A(b) specific CD4+ T cells were isolated from immunized knock-out mice and wild-type controls on day 7 post immunization and the gene expression profiles of the cells were compared Antigen-specifc CD4+ T cells were isolated and pooled from 4 independent experiments. The samples represent antige...
ORGANISM(S): Mus musculus 
2014-04-22 | E-GEOD-56966 | biostudies-arrayexpress
OtherA combined omics approach to generate the surface atlas of human naive CD4+ T cells during early TCR activation.
Data from ProteomeXchange, PXD ID: PXD001432. File: SUK5557A8MA2__008-Spender2_3hP SUK5557A8MA2-40-215297.mzml. Published as part of . From the Abstract: {{i}} ... Periodate oxidation and aniline-catalyzed oxime ligation (PAL) technology was applied with subsequent quantitative LC-MS/MS (PAL-qLC-MS...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310020145 | GPMDB
Resource Reanalysis 
ProteomicsLC-MS analysis of Murine eIF4E-BP1/2 Double Knockout naive and TCR stimulated CD4+ T cells
This project focuses on examining the differences in the global CD4+ T cell proteome between cells lacking the negative regulators of eIF4E( eIf4E-Binding Proteins 1/2) and WT naive CD4+ T cells both prior and following TCR stimulation.
ORGANISM(S): Mus musculus (Mouse) 
2023-05-20 | PXD039635 | Pride
Translational regulation Immunology Cd4+ t cells Murine Eif4e 
TranscriptomicsTranscription profiling of mouse CD4+ CD25+, CD4+ CD25- CD45RBlow LAG3+ and CD4+ CD25- CD45RBlow LAG3- T cells
Comparison of gene expression profile of CD4+ CD25+, CD4+ CD25- CD45RBlow LAG3+ and CD4+ CD25- CD45RBlow LAG3- T cells. Naive CD4+CD25-CD45RBhigh T cells were used as a reference for pair comparison with values from the three other subsets.
ORGANISM(S): Mus musculus 
2009-08-19 | E-MEXP-1343 | biostudies-arrayexpress
ProteomicsProject Title: Proteome analysis of CD4+ T cell subsets
Functionally distinct CD4+ helper T (Th) cell subsets, such as Th1, Th2, Th17, and regulatory T cells (Treg), play a pivotal role in the host-defense against pathogen invasion and the pathogenesis of inflammatory disorders. In this project, DIA-MS-based proteome analysis was performed on naïve CD4+ ...
ORGANISM(S): Mus Musculus (mouse) 
2023-01-04 | PXD036065 | JPOST Repository
TranscriptomicsAnalysis of miRNA profiles in CD4+ T-lymphocytes following exposure to HIV-1
Assessment of the extent to which the altered profiles of miRNA expression influence viral replication and latency, as well as the efficiency of host defenses, may be useful for understanding the basis of the HIV-1-related alterations in cellular physiology and immunologic control. To this end, thre...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-GEOD-33514 | biostudies-arrayexpress
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