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TranscriptomicsAre Non-animal Systemic Safety Assessments Protective: A Toolbox and Workflow
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15258 | biostudies-arrayexpress
UnknownScreening for prostate cancer with prostate-specific antigen testing: American Society of Clinical Oncology Provisional Clinical Opinion.
Not available
S-EPMC3776923 | biostudies-literature
TranscriptomicsFoxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation
CD4+ T follicular helper (Tfh) cells are essential for germinal center (GC) and high-affinity antibody responses. Yet the regulation that determines the initial development of Tfh cells is still largely unknown. Here we find that transcription factor Foxp1, previously shown to be essential in mainta...
ORGANISM(S): Mus musculus 
2014-05-18 | E-GEOD-50725 | biostudies-arrayexpress
TranscriptomicsThe Nicotinic alpha6 Subunit Gene Determines Variability in Chronic Pain Sensitivity and Nicotine Anti- allodynia via Cross-inhibition of P2X2/3 Receptors.
We used microarray-based expression genomics in 25 inbred mouse strains to identify dorsal root ganglion (DRG)-expressed genetic contributors to mechanical allodynia a prominent symptom of chronic pain. Expression genetics identifies a role for the Chrna6 (alpha 6-nicotinic receptor) gene in pain in...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-65997 | biostudies-arrayexpress
ProteomicsLongitudinal proteomic analysis of influenza HA-reactive IgG antibody repertoire over multiple years and repeated vaccinations
Longitudinal proteomic analysis of H1N1 A/California/7/2009 (CA09) hemagglutinin (HA)-reactive serum IgG antibody repertoire over 5 years and multiple (yearly) vaccinations (both pre- and post-vaccination samples) in a donor. Dataset consists of steady-state (pre-vaccination at day 0) and peak-respo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-11-08 | MSV000083120 | MassIVE
UnknownDeep learning acceleration of multiscale superresolution localization photoacoustic imaging.
Not available
S-EPMC9095876 | biostudies-literature
TranscriptomicsPulmonary retention of titanium dioxide nanoparticles and biological outcomes following low dose instillation in mice
Pulmonary exposure to high doses of nanoparticles (NP) leads to well characterized lung toxicity in addition to long-term NP retention. However, pulmonary NP accumulation and toxicity following low dose exposures are not well described. In the present study we sought to: (1) investigate particle ret...
ORGANISM(S): Mus musculus 
2013-11-01 | E-GEOD-41041 | biostudies-arrayexpress
ProteomicsProteomics study on caffeine for 10 min
Proteomics study on the HepG2 cells which were treated with 6 doses of caffeine for 10 min
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD030943 |
ProteomicsProteomics study on caffeine treated for 24 h
Proteomics study on the HepG2 cells which were treated with 6 doses of caffeine for 24 h
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD030946 |
ProteomicsPhosphoprotoemics study on caffeine for 24h
Phosphoproteomics study on the HepG2 cells which were treated with 6 doses of caffeine for 24 h
ORGANISM(S): Homo Sapiens 
2022-01-17 | PXD031005 |
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