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The global proteome analysis by liquid chromatography-mass spectrometry (LC-MS) has emerged as an important tool to study cell signalling. The effect of ITGB1 on imatinib resistance to leukemia was checked by comparing quantitative proteomic analysis of ITGB1-knockdown (ITGB1-KD) and ITGB1- vector c...
ORGANISM(S): Homo sapiens (Human) 
2025-10-30 | PXD057116 | Pride
K562 cells untreated (S) and treated (S+IM) with Imatinib as well as sensitive (S+IM) and resistant (R) to imatinib were subjected to labelled quantification by iTRAQ to identify Bcr-Abl downstream signaling components and proteins modulated in resistance respectively
ORGANISM(S): Homo sapiens (Human) 
2021-10-05 | PXD025173 | Pride
Comparative label free quantitative proteomic analysis using SWATH-MS has been carried out for K562 cells treated with Imatinib (S+IM) against untreated K562 (S) as well as imatinib resistant K562 cells (R). Compariosn of S+IM vs R constitutes Dataset 1 while that of S vs S+IM constitutes dataset 2
ORGANISM(S): Homo sapiens (Human) 
2019-06-14 | PXD009686 | Pride
Transcriptional profiling was utilized to define the biological pathways of gingival epithelial cells modulated by co-culture with the oral commensal S. gordonii and the opportunistic commensal F. nucleatum. We used microarrays to detail the global programme of gene expression underlying infection a...
ORGANISM(S): Homo sapiens 
The global phosphoproteome analysis by liquid chromatography-mass spectrometry (LC-MS) has emerged as an important tool to study cell signalling. However, the coverage of phosphoproteome by LC-MS is limited despite various approaches for phosphoprotein enrichment. Studies in literature have exploite...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Cercopithecus aethiops (Green monkey) (Grivet) Pinus radiata (Monterey pine) Drosophila melanogaster (Fruit fly) Caenorhabditis elegans Dictyostelium discoideum (Slime mold) Cicer arietinum (Chickpea) (Garbanzo) Bos taurus (Bovine) Candida albicans (Yeast) Homo sapiens (Human) Brassica oleracea var. botrytis (Cauliflower) Bombyx mori (Silk moth) Brassica napus (Rape) 
2025-10-30 | PXD057032 | Pride
Prognostication of Breast Cancer (BC) relies largely on traditional markers such as hormone or growth factors but due to their suboptimal specificities, it is challenging to identify the subset of patients who are likely to undergo recurrence and markers of higher specificity are sought to guide the...
ORGANISM(S): Homo sapiens 
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