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CcpA is a global regulator of transcription in Gram-positive bacteria that controls gene expression in response to carbohydrate availability. Using the fructan hydrolase (fruA) gene of S. mutans as a model, we demonstrate that CcpA does indeed play a major role in carbohydrate catabolite repression...
ORGANISM(S): Streptococcus mutans 
In this report, codY mutant strains were constructed and used to demonstrate the relationship of (p)ppGpp synthesized by RelP and RelQ with the activation of CodY. In addition, because CodY has not been studied in S. mutans, we used microarrays to demonstrate that this protein function as a global ...
ORGANISM(S): Streptococcus mutans 
The 15 strains of Gambierdiscus were cultivated in four separate laboratories. Each laboratory grew their available strains (see sample metadata) in addition to the G. australes strain AUS S080911_1 isolated from Pacific Ocean. Irradiance (70-100 umol photons m-2 s-1) and light/dark cycle (12h:12h)...
ORGANISM(S): Gambierdiscus Silvae (ncbitaxon:1550089) Gambierdiscus Carolinianus (ncbitaxon:864182) Gambierdiscus Australes (ncbitaxon:439317) Gambierdiscus Belizeanus (ncbitaxon:439316) Gambierdiscus Excentricus (ncbitaxon:986170) Gambierdiscus Caribaeus (ncbitaxon:864185) 
2024-02-26 | MSV000094172 | MassIVE
Discovery-based quantitative proteomics identified dozens of novel protein candidates in saliva, yet none are clinically qualified. Mass spectrometry (MS) has been recognized as newer 'gold standard' for the identification and analysis of individual proteins in complex biological samples due to high...
ORGANISM(S): Homo sapiens (Human) 
2019-12-20 | PXD015220 | Pride
Salivarian trypanosomes cause human sleeping sickness and economically important livestock diseases, transmitted by Tsetse flies and replicating extracellularly throughout the life cycle. The surface of "bloodstream forms", which live within mammals, is coated by a monolayer of a Variant Surface Gly...
ORGANISM(S): Trypanosoma brucei 
2021-04-14 | PXD021772 | Pride
Treatment of metastatic castration-resistant prostate cancer (mCRPC) remains clinically challenging due to tumor heterogeneity and drug resistance. Microtubule-targeting agents are a mainstay of mCRPC therapy, but limitations persist regarding progression-free survival. Pterocarpans have emerged as ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073655 | Pride
All above ground organs of higher plants are ultimately derived from shoot apical meristems (SAMs). The SAM exhibits distinctive structural organization, and monocot SAMs such as maize are comprised of two cell layers, a single cell layered tunica (L1) and a corpus (L2). Although recent research ha...
ORGANISM(S): Zea mays 
In the current work, saliva samples were collected from children with different degrees of ASD and healthy children and proteomics approaches were applied to generate data on differentially expressed proteins between groups which will serve as a basis for future validation studies as protein markers...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD030065 | Pride
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