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ProteomicsEffect of starvation conditions on cultured human H4 neuroglioma cells stably expressing shLuc and shATG5
An attempt to analyse a large proportion of the human proteome of cultured Human H4 neuroglioma cells during conditions simulating starvation. Comparisons were made under conditions of ATG5 knock-down and control (Luc) knock-down. Whole proteome crude extracts were prepared and comparisons made usin...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD024486 | Pride
Atg5 Cultured human cells Starvation 
GenomicsGene expression changes in human neuroglioma cell line H4 upon stress induction with sorbitol or thapsigargin
Gene expression changes in human neuroglioma cell line H4 upon stress induction with sorbitol or thapsigargin
PRJNA1470642 | ENA
TranscriptomicsGene expression changes in human neuroglioma cell line H4 upon stress induction with sorbitol or thapsigargin
We found that stress induction with sorbitol or thapsigargin in neurons including human neuroglioma cell line H4 leads to the rapid degradation of FMRP. To reveal mechanisms involved, we used Clariom S Assays to identify gene expression changes shared by sorbitol and thapsigargin treated H4 cells.
ORGANISM(S): Homo sapiens 
2026-09-01 | GSE333295 | GEO
UnknownPCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.
Not available
S-EPMC4440094 | biostudies-literature
UnknownORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells.
Not available
S-EPMC7432374 | biostudies-literature
UnknownSeventy-Two-Hour LRRK2 Kinase Activity Inhibition Increases Lysosomal GBA Expression in H4, a Human Neuroglioma Cell Line.
Not available
S-EPMC9266636 | biostudies-literature
UnknownStress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure.
Not available
S-EPMC11580520 | biostudies-literature
TranscriptomicsAmyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer’s disease model cell line.
Genome wide DNA methylation profiling of human neuroglioma cell line (H4) and the Swedish double mutant-harboring H4 cell line (H4-sw). The Illumina Infinium 27k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 27,000 CpGs in 2 cell lines, H4 and H4-sw....
ORGANISM(S): Homo sapiens 
2015-09-06 | E-GEOD-72538 | biostudies-arrayexpress
ProteomicsMultiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health
Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling late-stage maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases, manif...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041323 | Pride
Human Lysoip Neuroglioma Whole cell proteome H4 Retromer Secretome Cell surface proteome Lc-ms/ms 
Methylation profilingAmyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer’s disease model cell line.
Genome wide DNA methylation profiling of human neuroglioma cell line (H4) and the Swedish double mutant-harboring H4 cell line (H4-sw). The Illumina Infinium 27k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 27,000 CpGs in 2 cell lines, H4 and H4-sw.
ORGANISM(S): Homo sapiens 
2015-09-06 | GSE72538 | GEO
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